Predicted to enable proton-transporting ATPase activity, rotational mechanism. Predicted to be involved in several processes, including regulation of pH; synaptic vesicle lumen acidification; and vacuolar proton-transporting V-type ATPase complex assembly. Predicted to act upstream of or within several processes, including renal sodium excretion; renal sodium ion transport; and renal water homeostasis. Located in apical plasma membrane and basolateral plasma membrane. Is extrinsic component of synaptic vesicle membrane. Human ortholog(s) of this gene implicated in renal tubular acidosis. Orthologous to human ATP6V1B1 (ATPase H+ transporting V1 subunit B1).
RGD Description
Predicted to enable proton-transporting ATPase activity, rotational mechanism. Predicted to be involved in several processes, including regulation of pH; synaptic vesicle lumen acidification; and vacuolar proton-transporting V-type ATPase complex assembly. Predicted to act upstream of or within several processes, including renal sodium excretion; renal sodium ion transport; and renal water homeostasis. Located in apical plasma membrane and basolateral plasma membrane. Is extrinsic component of synaptic vesicle membrane. Human ortholog(s) of this gene implicated in renal tubular acidosis. Orthologous to human ATP6V1B1 (ATPase H+ transporting V1 subunit B1); PARTICIPATES IN oxidative phosphorylation pathway; phagocytosis pathway; rheumatoid arthritis pathway; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,3,7,8-Tetrachlorodibenzofuran; 4,4'-sulfonyldiphenol.