Gene

Atp6v1b1

Species
Rattus norvegicus
Symbol
Atp6v1b1
Name
ATPase H+ transporting V1 subunit B1
Synonyms
  • ATPase, H transporting, lysosomal V1 subunit B1
  • ATPase, H+ transporting, V1 subunit B
Biotype
protein coding gene
Automated Description
Predicted to enable proton-transporting ATPase activity, rotational mechanism. Predicted to be involved in several processes, including regulation of pH; synaptic vesicle lumen acidification; and vacuolar proton-transporting V-type ATPase complex assembly. Predicted to act upstream of or within several processes, including renal sodium excretion; renal sodium ion transport; and renal water homeostasis. Located in apical plasma membrane and basolateral plasma membrane. Is extrinsic component of synaptic vesicle membrane. Human ortholog(s) of this gene implicated in renal tubular acidosis. Orthologous to human ATP6V1B1 (ATPase H+ transporting V1 subunit B1).
RGD Description
Predicted to enable proton-transporting ATPase activity, rotational mechanism. Predicted to be involved in several processes, including regulation of pH; synaptic vesicle lumen acidification; and vacuolar proton-transporting V-type ATPase complex assembly. Predicted to act upstream of or within several processes, including renal sodium excretion; renal sodium ion transport; and renal water homeostasis. Located in apical plasma membrane and basolateral plasma membrane. Is extrinsic component of synaptic vesicle membrane. Human ortholog(s) of this gene implicated in renal tubular acidosis. Orthologous to human ATP6V1B1 (ATPase H+ transporting V1 subunit B1); PARTICIPATES IN oxidative phosphorylation pathway; phagocytosis pathway; rheumatoid arthritis pathway; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,3,7,8-Tetrachlorodibenzofuran; 4,4'-sulfonyldiphenol.
Cross References
Additional Information
Literature

Orthology

Gene tree
PANTHER:PTHR43389
Links to orthology data in JBrowse by filter level: Stringent,  Moderate,  No filter,  Best and Best Reverse

Paralogy

Function - GO Annotations

Pathways

No data available

Phenotypes

Primary Sources
None
Other Sources
None

Disease Associations

Cases where the expected disease association was NOT found
Cell color indicative of annotation volume

Transgenic Alleles

Models

Sequence Feature Viewer

Genome location
Assembly version
mRatBN7.2
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116.224M116.226M116.228M116.230M116.232M116.234M116.236M116.238M116.240M116.242M

Sequence Details

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Expression

Primary Sources
None
Other Sources
Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

Molecular Interactions

Genetic Interactions