Version: 8.0.0
Date: Tue Jan 28 2025
Ifi30
Rattus norvegicusRGD:1310758
SummaryOrthologyParalogyFunction - GO AnnotationsPathwaysPhenotypesDisease AssociationsAlleles and VariantsTransgenic AllelesModelsSequence Feature ViewerSequence DetailsExpressionMolecular InteractionsGenetic Interactions
Gene

Ifi30

Species
Rattus norvegicus
Symbol
Ifi30
Name
IFI30, lysosomal thiol reductase
Synonyms
  • gamma-interferon-inducible lysosomal thiol reductase
  • interferon gamma inducible protein 30
Biotype
protein coding gene
Automated Description
Predicted to enable oxidoreductase activity, acting on a sulfur group of donors. Predicted to be involved in antigen processing and presentation of exogenous peptide antigen via MHC class I. Predicted to act upstream of or within antigen processing and presentation of exogenous peptide antigen via MHC class II; negative regulation of fibroblast proliferation; and protein stabilization. Predicted to be located in cell junction; cytosol; and intracellular membrane-bounded organelle. Predicted to be active in lysosome. Orthologous to human IFI30 (IFI30 lysosomal thiol reductase).
RGD Description
Predicted to enable oxidoreductase activity, acting on a sulfur group of donors. Predicted to be involved in antigen processing and presentation of exogenous peptide antigen via MHC class I. Predicted to act upstream of or within antigen processing and presentation of exogenous peptide antigen via MHC class II; negative regulation of fibroblast proliferation; and protein stabilization. Predicted to be located in cell junction; cytosol; and intracellular membrane-bounded organelle. Predicted to be active in lysosome. Orthologous to human IFI30 (IFI30 lysosomal thiol reductase); PARTICIPATES IN antigen processing and presentation pathway; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,4,6-trinitrobenzenesulfonic acid; 2,6-dinitrotoluene.
Cross References
Additional Information
Literature

Orthology

Gene tree
PANTHER:PTHR13234
Links to orthology data in JBrowse by filter level: Stringent,  Moderate,  No filter,  Best and Best Reverse

Paralogy

Function - GO Annotations

Pathways

No data available

Phenotypes

Primary Sources
None
Other Sources
None
Phenotype Term
Annotation details
References
No records match query. Try removing filters.
Showing 0 - 0 of 0 rows
per page

    Disease Associations

    Cases where the expected disease association was NOT found
    Cell color indicative of annotation volume
    No data available

    Alleles and Variants

    Allele/Variant Symbol
    Allele Synonyms
    Category
    Variant
    Variant type
    Molecular consequence
    Has Disease Annotations
    Has Phenotype Annotations
    No records match query. Try removing filters.
    Showing 0 - 0 of 0 rows
    per page
      Download all Alleles/Variants for all genes of the species

      Transgenic Alleles

      Species
      (carrying the transgene)
      Allele symbol
      Transgenic construct
      Expressed components
      Knock-down targets
      Regulatory regions
      Has Disease Annotations
      Has Phenotype Annotations
      No records match query. Try removing filters.
      Showing 0 - 0 of 0 rows
      per page

        Models

        Model name
        Experimental condition
        Associated Human Diseases
        Associated Phenotypes
        Modifier
        Source
        No records match query. Try removing filters.
        Showing 0 - 0 of 0 rows
        per page

          Sequence Feature Viewer

          Genome location
          Assembly version
          mRatBN7.2
          Viewer Help
          Data currently unavailable; sequence viewer under construction

          Sequence Details

          Loading...

          Expression

          Primary Sources
          None
          Other Sources
          Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

          Molecular Interactions

          Ifi30 molecule type
          Interactor gene
          Interactor species
          Interactor molecule type
          Detection methods
          Source
          Reference
          No records match query. Try removing filters.
          Showing 0 - 0 of 0 rows
          per page

            Genetic Interactions

            Ifi30 role
            Ifi30 genetic perturbation
            Interactor gene
            Interactor species
            Interactor role
            Interactor genetic perturbation
            Interaction type
            Phenotype or trait
            Source
            Reference
            No records match query. Try removing filters.
            Showing 0 - 0 of 0 rows
            per page