Gene

Rras2

Species
Rattus norvegicus
Symbol
Rras2
Name
RAS related 2
Synonyms
  • LOC365355
  • MGC109327
Biotype
protein coding gene
Automated Description
Predicted to enable GDP binding activity; GTP binding activity; and GTPase activity. Predicted to act upstream of or within Ras protein signal transduction and positive regulation of Schwann cell migration. Predicted to be located in endomembrane system. Predicted to be active in plasma membrane. Human ortholog(s) of this gene implicated in Noonan syndrome 12. Orthologous to human RRAS2 (RAS related 2).
RGD Description
Predicted to enable GDP binding activity; GTP binding activity; and GTPase activity. Predicted to act upstream of or within Ras protein signal transduction and positive regulation of Schwann cell migration. Predicted to be active in plasma membrane. Human ortholog(s) of this gene implicated in Noonan syndrome 12. Orthologous to human RRAS2 (RAS related 2); PARTICIPATES IN mitogen activated protein kinase signaling pathway; INTERACTS WITH (+)-schisandrin B; 1,3-dinitrobenzene; 2,3,7,8-tetrachlorodibenzodioxine.
Cross References
Additional Information
Literature

Orthology

Gene tree
PANTHER:PTHR24070
Stringency:
Additional filters to further constrain the results:
Species Gene symbol Count Best Best reverse
Method
Ensembl ComparaHGNCHieranoidInParanoidOMAOrthoFinderOrthoInspectorPANTHERPhylomeDBSonicParanoidXenbaseZFIN
Homo sapiensRRAS210 of 10YesYes  
Mus musculusRras29 of 9YesYes   
Xenopus tropicalisrras6 of 9YesYes   
Danio reriorras29 of 9YesYes   
Drosophila melanogasterRas64B8 of 9YesYes   
Caenorhabditis elegansras-18 of 9YesYes   
Saccharomyces cerevisiaeRAS17 of 9YesYes   
Saccharomyces cerevisiaeRAS27 of 9YesYes   
Links to orthology data in JBrowse by filter level: Stringent,  Moderate,  No filter,  Best and Best Reverse

Paralogy

Gene symbolRank Alignment Length (aa) Similarity %Identity %Method Count
Method
Ensembl ComparaHGNCInParanoidOMAOrthoFinderOrthoInspectorPANTHERPhylomeDBSonicParanoidSGD
Rras119979667 of 9 
Mras220172563 of 9 
Kras319471544 of 9 
Hras419070554 of 9 
Nras519370534 of 9 
Rap1b618771514 of 9 
Rap1a718571514 of 9 
Rap2b819266444 of 9 
Rit1919667493 of 9 
Ralb1019966473 of 9 
Rap2c1117570464 of 9 
Rala1218270493 of 9 
Rit21316770543 of 9 
Eras1420455383 of 9 
Rerg1516366453 of 9 
Rasl121620353343 of 9 
Diras21718956383 of 9 
Diras11818457383 of 9 
Diras31917760333 of 9 
Rem22020655322 of 9 
Rasd12118855382 of 9 
Rheb2216260373 of 9 
Rasd22319551372 of 9 
Gem2419356332 of 9 
Rem12520052312 of 9 
Rasl11a2620748312 of 9 
Rasl11b2718952312 of 9 
Nkiras12819149322 of 9 
Rrad2919150312 of 9 
Rergl3018853302 of 9 
Rap2a3110276513 of 9 
Nkiras23218349282 of 9 
Rhebl1339461343 of 9 

Function - GO Annotations

Pathways

No data available

Phenotypes

Primary Sources
None
Other Sources
None
No data available

Disease Associations

Cases where the expected disease association was NOT found
Must provide at least one subject
Cell color indicative of annotation volume

Alleles and Variants

No mapped variant information available
Allele/Variant Symbol
Allele Synonyms
Category
Variant
Variant type
Molecular consequence
Has Disease Annotations
Has Phenotype Annotations
NC_051336.1:g.168262904T>Avariant
SNP
  • intron variant
NC_051336.1:g.168272715G>Avariant
SNP
  • intron variant
NC_051336.1:g.168276077A>Gvariant
SNP
  • intron variant
NC_051336.1:g.168276238T>Cvariant
SNP
  • intron variant
NC_051336.1:g.168258162T>Cvariant
SNP
  • intron variant
NC_051336.1:g.168258530C>Tvariant
SNP
  • intron variant
NC_051336.1:g.168255055T>Cvariant
NC_051336.1:g.168266680A>Gvariant
SNP
  • intron variant
NC_051336.1:g.168286882G>Avariant
NC_051336.1:g.168235672A>Gvariant
SNP
  • intron variant
Showing 1 - 10 of 307 rows
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Transgenic Alleles

No data available

Models

Sequence Feature Viewer

Genome location
Assembly version
mRatBN7.2
Viewer Help
168.24M168.25M168.26M168.27M168.28M168.29M168.30M

Sequence Details

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Expression

Primary Sources
None
Other Sources
Must provide at least one subject
Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

Molecular Interactions

1 interactor gene based on 1 annotation
Rras2 molecule type
Interactor gene
Interactor species
Interactor molecule type
Detection methods
Source
Reference
protein
RNF207Homo sapiens
protein
  • affinity chromatography technology
PMID:35352799
Showing 1 - 1 of 1 rows
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Genetic Interactions

No data available