Gene

Usp45

Species
Rattus norvegicus
Symbol
Usp45
Name
ubiquitin specific peptidase 45
Synonyms
  • LOC313098
  • ubiquitin carboxyl-terminal hydrolase 45
Biotype
protein coding gene
Automated Description
Predicted to enable cysteine-type deubiquitinase activity. Predicted to be involved in cell migration and photoreceptor cell maintenance. Predicted to act upstream of or within DNA repair and protein deubiquitination. Predicted to be located in cytosol; nucleoplasm; and photoreceptor inner segment. Human ortholog(s) of this gene implicated in Leber congenital amaurosis 19. Orthologous to human USP45 (ubiquitin specific peptidase 45).
RGD Description
Predicted to enable cysteine-type deubiquitinase activity. Predicted to be involved in cell migration and photoreceptor cell maintenance. Predicted to act upstream of or within DNA repair and protein deubiquitination. Predicted to be located in cytosol; nucleoplasm; and photoreceptor inner segment. Human ortholog(s) of this gene implicated in Leber congenital amaurosis 19. Orthologous to human USP45 (ubiquitin specific peptidase 45); INTERACTS WITH 17alpha-ethynylestradiol; 2,3,7,8-tetrachlorodibenzodioxine; 3,4-methylenedioxymethamphetamine.
Cross References
Additional Information
Literature

Orthology

Gene tree
PANTHER:PTHR21646
Links to orthology data in JBrowse by filter level: Stringent,  Moderate,  No filter,  Best and Best Reverse

Paralogy

Function - GO Annotations

Pathways

No data available

Phenotypes

Primary Sources
None
Other Sources
None

Disease Associations

Cases where the expected disease association was NOT found
Cell color indicative of annotation volume

Transgenic Alleles

Models

Sequence Feature Viewer

Genome location
Assembly version
mRatBN7.2
Viewer Help
35.32M35.33M35.34M35.35M35.36M35.37M35.38M35.39M

Sequence Details

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Expression

Primary Sources
None
Other Sources
Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

Molecular Interactions

Genetic Interactions