Gene

Brms1

Species
Rattus norvegicus
Symbol
Brms1
Name
BRMS1, transcriptional repressor and anoikis regulator
Synonyms
  • breast cancer metastasis suppressor 1
  • breast cancer metastasis-suppressor 1
Biotype
protein coding gene
Automated Description
Predicted to enable NF-kappaB binding activity and histone deacetylase binding activity. Predicted to be involved in positive regulation of anoikis; positive regulation of protein deacetylation; and regulation of DNA-templated transcription. Predicted to be located in cytoplasm and nucleus. Predicted to be part of Sin3-type complex. Orthologous to human BRMS1 (BRMS1 transcriptional repressor and anoikis regulator).
RGD Description
Predicted to enable NF-kappaB binding activity and histone deacetylase binding activity. Predicted to be involved in positive regulation of anoikis; positive regulation of protein deacetylation; and regulation of DNA-templated transcription. Predicted to be located in cytoplasm and nucleus. Predicted to be part of Sin3-type complex. Orthologous to human BRMS1 (BRMS1 transcriptional repressor and anoikis regulator); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; paraquat; Soman.
Cross References
Additional Information
Literature

Orthology

Gene tree
PANTHER:PTHR21964
Links to orthology data in JBrowse by filter level: Stringent,  Moderate,  No filter,  Best and Best Reverse

Paralogy

Function - GO Annotations

Pathways

No data available

Phenotypes

Primary Sources
None
Other Sources
None

Disease Associations

Cases where the expected disease association was NOT found
Cell color indicative of annotation volume

Transgenic Alleles

Models

Sequence Feature Viewer

Genome location
Assembly version
mRatBN7.2
Viewer Help
202.346M202.347M202.348M202.349M202.350M202.351M202.352M202.353M202.354M202.355M

Sequence Details

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Expression

Primary Sources
None
Other Sources
Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

Molecular Interactions

Genetic Interactions