Gene

Brms1

Species
Rattus norvegicus
Symbol
Brms1
Name
BRMS1, transcriptional repressor and anoikis regulator
Synonyms
  • breast cancer metastasis suppressor 1
  • breast cancer metastasis-suppressor 1
Biotype
protein coding gene
Automated Description
Predicted to enable NF-kappaB binding activity and histone deacetylase binding activity. Predicted to be involved in positive regulation of anoikis; positive regulation of protein deacetylation; and regulation of DNA-templated transcription. Predicted to be located in cytoplasm and nucleus. Predicted to be part of Sin3-type complex. Orthologous to human BRMS1 (BRMS1 transcriptional repressor and anoikis regulator).
RGD Description
Predicted to enable NF-kappaB binding activity and histone deacetylase binding activity. Predicted to be involved in positive regulation of anoikis; positive regulation of protein deacetylation; and regulation of DNA-templated transcription. Predicted to be located in cytoplasm and nucleus. Predicted to be part of Sin3-type complex. Orthologous to human BRMS1 (BRMS1 transcriptional repressor and anoikis regulator); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; paraquat; Soman.
Cross References
Additional Information
Literature

Orthology

Gene tree
PANTHER:PTHR21964
Stringency:
Additional filters to further constrain the results:
Species Gene symbol Count Best Best reverse
Method
Ensembl ComparaHGNCHieranoidInParanoidOMAOrthoFinderOrthoInspectorPANTHERPhylomeDBSonicParanoidXenbaseZFIN
Homo sapiensBRMS110 of 10YesYes  
Mus musculusBrms19 of 9YesYes   
Xenopus tropicalisbrms18 of 9YesYes   
Danio reriobrms17 of 9YesYes   
Drosophila melanogasterBrms19 of 9YesYes   
Links to orthology data in JBrowse by filter level: Stringent,  Moderate,  No filter,  Best and Best Reverse

Paralogy

Gene symbolRank Alignment Length (aa) Similarity %Identity %Method Count
Method
Ensembl ComparaHGNCInParanoidOMAOrthoFinderOrthoInspectorPANTHERPhylomeDBSonicParanoidSGD
Brms1l125174557 of 9 
Suds3224049243 of 9 

Function - GO Annotations

Pathways

No data available

Phenotypes

Primary Sources
None
Other Sources
None
No data available

Disease Associations

Cases where the expected disease association was NOT found
Must provide at least one subject
Cell color indicative of annotation volume
No data available

Alleles and Variants

Allele/Variant Symbol
Allele Synonyms
Category
Variant
Variant type
Molecular consequence
Has Disease Annotations
Has Phenotype Annotations
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    Transgenic Alleles

    No data available

    Models

    No data available

    Sequence Feature Viewer

    Genome location
    Assembly version
    mRatBN7.2
    Viewer Help
    Data currently unavailable; sequence viewer under construction

    Sequence Details

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    Expression

    Primary Sources
    None
    Other Sources
    Must provide at least one subject
    Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

    Molecular Interactions

    Brms1 molecule type
    Interactor gene
    Interactor species
    Interactor molecule type
    Detection method
    Source
    Reference
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      Genetic Interactions

      Brms1 role
      Brms1 genetic perturbation
      Interactor gene
      Interactor species
      Interactor role
      Interactor genetic perturbation
      Interaction type
      Phenotype or trait
      Source
      Reference
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