Gene

Il36rn

Species
Rattus norvegicus
Symbol
Il36rn
Name
interleukin 36 receptor antagonist
Synonyms
  • Il1f5
  • interleukin 1 family, member 5 (delta)
Biotype
protein coding gene
Automated Description
Predicted to enable cytokine activity and interleukin-1 receptor binding activity. Predicted to be involved in several processes, including antifungal humoral response; cellular response to lipopolysaccharide; and negative regulation of cytokine production. Predicted to act upstream of or within negative regulation of interleukin-6 production. Predicted to be active in extracellular space. Human ortholog(s) of this gene implicated in pustular psoriasis 14. Orthologous to human IL36RN (interleukin 36 receptor antagonist).
RGD Description
Predicted to enable cytokine activity and interleukin-1 receptor binding activity. Predicted to be involved in several processes, including antifungal humoral response; cellular response to lipopolysaccharide; and negative regulation of cytokine production. Predicted to act upstream of or within negative regulation of interleukin-6 production. Predicted to be active in extracellular space. Human ortholog(s) of this gene implicated in pustular psoriasis 14. Orthologous to human IL36RN (interleukin 36 receptor antagonist); INTERACTS WITH 4,4'-sulfonyldiphenol; acrylamide; astemizole.
Cross References
Additional Information
Literature

Orthology

Gene tree
PANTHER:PTHR10078
Links to orthology data in JBrowse by filter level: Stringent,  Moderate,  No filter,  Best and Best Reverse

Paralogy

Function - GO Annotations

Pathways

No data available

Phenotypes

Primary Sources
Other Sources
None

Disease Associations

Cases where the expected disease association was NOT found
Cell color indicative of annotation volume

Transgenic Alleles

Models

Sequence Feature Viewer

Genome location
Assembly version
mRatBN7.2
Viewer Help
7.045M7.046M7.047M7.048M7.049M7.050M7.051M

Sequence Details

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Expression

Primary Sources
None
Other Sources
Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

Molecular Interactions

Genetic Interactions