Gene

Lin54

Species
Rattus norvegicus
Symbol
Lin54
Name
lin-54 DREAM MuvB core complex component
Synonyms
  • lin-54 homolog (C. elegans)
  • LOC305171
Biotype
protein coding gene
Automated Description
Predicted to enable minor groove of adenine-thymine-rich DNA binding activity and transcription regulatory region nucleic acid binding activity. Predicted to be involved in regulation of DNA-templated transcription. Predicted to act upstream of or within nucleosome organization. Predicted to be part of RNA polymerase II transcription repressor complex. Predicted to be active in nucleus. Orthologous to human LIN54 (lin-54 DREAM MuvB core complex component).
RGD Description
Predicted to enable minor groove of adenine-thymine-rich DNA binding activity and transcription regulatory region nucleic acid binding activity. Predicted to be involved in regulation of DNA-templated transcription. Predicted to act upstream of or within nucleosome organization. Predicted to be part of RNA polymerase II transcription repressor complex. Predicted to be active in nucleus. Orthologous to human LIN54 (lin-54 DREAM MuvB core complex component); INTERACTS WITH bisphenol A; cadmium dichloride; cobalt dichloride.
Cross References
Additional Information
Literature

Orthology

Gene tree
PANTHER:PTHR12446
Stringency:
Additional filters to further constrain the results:
Species Gene symbol Count Best Best reverse
Method
Ensembl ComparaHGNCHieranoidInParanoidOMAOrthoFinderOrthoInspectorPANTHERPhylomeDBSonicParanoidXenbaseZFIN
Homo sapiensLIN5410 of 10YesYes  
Mus musculusLin549 of 9YesYes   
Xenopus tropicalislin549 of 9YesYes   
Danio reriolin548 of 9YesYes   
Drosophila melanogastermip1206 of 9YesYes   
Caenorhabditis eleganslin-545 of 9YesYes   
Links to orthology data in JBrowse by filter level: Stringent,  Moderate,  No filter,  Best and Best Reverse

Paralogy

Gene symbolRank Alignment Length (aa) Similarity %Identity %Method Count
Method
Ensembl ComparaHGNCInParanoidOMAOrthoFinderOrthoInspectorPANTHERPhylomeDBSonicParanoidSGD
Tesmin152048345 of 9 

Function - GO Annotations

No function available for that gene

Pathways

No data available

Phenotypes

Primary Sources
None
Other Sources
None
No data available

Disease Associations

Cases where the expected disease association was NOT found
Must provide at least one subject
Cell color indicative of annotation volume

Alleles and Variants

Genome location
Assembly version
mRatBN7.2
Viewer Help
9.13M9.14M9.15M9.16M9.17M9.18M
Variant Types and ConsequencesOnly variants associated to alleles are shown in the graphics above. See all variants in JBrowse.
Allele/Variant Symbol
Allele Synonyms
Category
Variant
Variant type
Molecular consequence
Has Disease Annotations
Has Phenotype Annotations
NC_051349.1:g.9138689C>Tvariant
SNP
  • intron variant
NC_051349.1:g.9133857G>Tvariant
SNP
  • intron variant
NC_051349.1:g.9136302G>Cvariant
SNP
  • intron variant
NC_051349.1:g.9137198A>Cvariant
SNP
  • intron variant
NC_051349.1:g.9139459A>Gvariant
SNP
  • intron variant
NC_051349.1:g.9151352T>Cvariant
SNP
  • intron variant
NC_051349.1:g.9170363C>Tvariant
SNP
  • intron variant
NC_051349.1:g.9161327T>Cvariant
SNP
  • intron variant
NC_051349.1:g.9177068T>Cvariant
SNP
  • synonymous variant
NC_051349.1:g.9165136G>Avariant
SNP
  • intron variant
Showing 1 - 10 of 156 rows
per page

Transgenic Alleles

No data available

Models

No data available

Sequence Feature Viewer

Genome location
Assembly version
mRatBN7.2
Viewer Help
9.13M9.14M9.15M9.16M9.17M9.18MENSRNOT00000003006.6 (Lin54)ENSRNOT00000102075.1 (Lin54)ENSRNOT00000106801.1 (Lin54)ENSRNOT00000109020.1 (Lin54)ENSRNOT00000119980.1 (Lin54)NM_001100564.1 (Lin54)XM_006250657.5 (Lin54)XM_006250658.5 (Lin54)XM_006250659.5 (Lin54)XM_006250661.5 (Lin54)Maximum features displayed. See full view for more.Maximum features displayed. See full view for more.Maximum features displayed. See full view for more.Maximum features displayed. See full view for more.

Sequence Details

Transcript: Mode:

Expression

Primary Sources
None
Other Sources
Must provide at least one subject
Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

Molecular Interactions

No data available

Genetic Interactions

No data available