Gene

Prss3

Species
Rattus norvegicus
Symbol
Prss3
Name
serine protease 3
Synonyms
  • LOC362347
  • protease, serine 3
Biotype
protein coding gene
Automated Description
Predicted to enable calcium ion binding activity and serine-type endopeptidase activity. Predicted to be involved in endothelial cell migration and zymogen activation. Predicted to be active in extracellular space. Human ortholog(s) of this gene implicated in pancreatitis. Orthologous to several human genes including PRSS3P2 (PRSS3 pseudogene 2); PRSS1 (serine protease 1); and PRSS2 (serine protease 2).
RGD Description
Predicted to enable calcium ion binding activity and serine-type endopeptidase activity. Predicted to be involved in endothelial cell migration and zymogen activation. Predicted to be active in extracellular space. Human ortholog(s) of this gene implicated in pancreatitis. Orthologous to several human genes including PRSS3P2 (PRSS3 pseudogene 2); PRSS1 (serine protease 1); and PRSS2 (serine protease 2); PARTICIPATES IN influenza A pathway; INTERACTS WITH 2,2',5,5'-tetrachlorobiphenyl; acrylamide; amphetamine.
Cross References
Additional Information
Literature

Orthology

Gene tree
PANTHER:PTHR24264
Links to orthology data in JBrowse by filter level: Stringent,  Moderate,  No filter,  Best and Best Reverse

Paralogy

Function - GO Annotations

Pathways

No data available

Phenotypes

Primary Sources
None
Other Sources
None

Disease Associations

Cases where the expected disease association was NOT found
Cell color indicative of annotation volume

Transgenic Alleles

Models

Sequence Feature Viewer

Genome location
Assembly version
mRatBN7.2
Viewer Help
70.2035M70.2040M70.2045M70.2050M70.2055M70.2060M70.2065M

Sequence Details

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Expression

Primary Sources
None
Other Sources
Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

Molecular Interactions

Genetic Interactions