Version: 8.0.0
Date: Tue Jan 28 2025
Eif3e
Rattus norvegicusRGD:1311521
SummaryOrthologyParalogyFunction - GO AnnotationsPathwaysPhenotypesDisease AssociationsAlleles and VariantsTransgenic AllelesModelsSequence Feature ViewerSequence DetailsExpressionMolecular InteractionsGenetic Interactions
Gene

Eif3e

Species
Rattus norvegicus
Symbol
Eif3e
Name
eukaryotic translation initiation factor 3 subunit E
Synonyms
  • eIF-3 p48
  • Eif3el1
Biotype
protein coding gene
Automated Description
Enables transmembrane transporter binding activity. Involved in intracellular calcium ion homeostasis and positive regulation of intracellular protein transport. Predicted to be located in PML body and cytosol. Predicted to be part of eukaryotic translation initiation factor 3 complex. Predicted to be active in nucleus and postsynaptic density. Used to study intermittent claudication. Orthologous to human EIF3E (eukaryotic translation initiation factor 3 subunit E).
RGD Description
Enables transmembrane transporter binding activity. Involved in intracellular calcium ion homeostasis and positive regulation of intracellular protein transport. Predicted to be located in PML body and cytosol. Predicted to be part of eukaryotic translation initiation factor 3 complex. Predicted to be active in nucleus and postsynaptic density. Used to study intermittent claudication. Orthologous to human EIF3E (eukaryotic translation initiation factor 3 subunit E); PARTICIPATES IN hypoxia inducible factor pathway; translation initiation pathway; hepatitis C pathway; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 4,4'-sulfonyldiphenol; bisphenol A.
Cross References
Additional Information
Literature

Orthology

Gene tree
PANTHER:PTHR10317
Links to orthology data in JBrowse by filter level: Stringent,  Moderate,  No filter,  Best and Best Reverse

Paralogy

Function - GO Annotations

Pathways

No data available

Phenotypes

Primary Sources
None
Other Sources
None
Phenotype Term
Annotation details
References
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    Disease Associations

    Cases where the expected disease association was NOT found
    Cell color indicative of annotation volume
    No data available

    Alleles and Variants

    Allele/Variant Symbol
    Allele Synonyms
    Category
    Variant
    Variant type
    Molecular consequence
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      Transgenic Alleles

      Species
      (carrying the transgene)
      Allele symbol
      Transgenic construct
      Expressed components
      Knock-down targets
      Regulatory regions
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      Has Phenotype Annotations
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        Models

        Model name
        Experimental condition
        Associated Human Diseases
        Associated Phenotypes
        Modifier
        Source
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          Sequence Feature Viewer

          Genome location
          Assembly version
          mRatBN7.2
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          Data currently unavailable; sequence viewer under construction

          Sequence Details

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          Expression

          Primary Sources
          None
          Other Sources
          Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

          Molecular Interactions

          Eif3e molecule type
          Interactor gene
          Interactor species
          Interactor molecule type
          Detection methods
          Source
          Reference
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            Genetic Interactions

            Eif3e role
            Eif3e genetic perturbation
            Interactor gene
            Interactor species
            Interactor role
            Interactor genetic perturbation
            Interaction type
            Phenotype or trait
            Source
            Reference
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