Gene

Vps18

Species
Rattus norvegicus
Symbol
Vps18
Name
VPS18 core subunit of CORVET and HOPS complexes
Synonyms
  • LOC296083
  • vacuolar protein sorting 18 (yeast)
Biotype
protein coding gene
Automated Description
Predicted to enable several functions, including actin binding activity; syntaxin binding activity; and ubiquitin protein ligase activity. Predicted to be involved in several processes, including endosome to lysosome transport; negative regulation of intracellular estrogen receptor signaling pathway; and vesicle docking involved in exocytosis. Predicted to act upstream of or within symbiont entry into host cell. Is active in presynapse. Orthologous to human VPS18 (VPS18 core subunit of CORVET and HOPS complexes).
RGD Description
Predicted to enable several functions, including actin binding activity; syntaxin binding activity; and ubiquitin protein ligase activity. Predicted to be involved in several processes, including endosome to lysosome transport; negative regulation of intracellular estrogen receptor signaling pathway; and vesicle docking involved in exocytosis. Predicted to act upstream of or within symbiont entry into host cell. Is active in presynapse. Orthologous to human VPS18 (VPS18 core subunit of CORVET and HOPS complexes); INTERACTS WITH 4,4'-sulfonyldiphenol; bisphenol A; bisphenol F.
Cross References
Additional Information
Literature

Orthology

Gene tree
PANTHER:PTHR23323
Links to orthology data in JBrowse by filter level: Stringent,  Moderate,  No filter,  Best and Best Reverse

Paralogy

Function - GO Annotations

Pathways

No data available

Phenotypes

Primary Sources
None
Other Sources
None

Disease Associations

Cases where the expected disease association was NOT found
Cell color indicative of annotation volume

Transgenic Alleles

Models

Sequence Feature Viewer

Genome location
Assembly version
mRatBN7.2
Viewer Help
106.280M106.282M106.284M106.286M106.288M106.290M

Sequence Details

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Expression

Primary Sources
None
Other Sources
Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

Molecular Interactions

Genetic Interactions