Gene

Wwp1

Species
Rattus norvegicus
Symbol
Wwp1
Name
WW domain containing E3 ubiquitin protein ligase 1
Synonyms
  • LOC297930
  • NEDD4-like E3 ubiquitin-protein ligase WWP1
Biotype
protein coding gene
Automated Description
Predicted to enable ubiquitin protein ligase activity. Predicted to be involved in negative regulation of DNA-templated transcription; proteasome-mediated ubiquitin-dependent protein catabolic process; and protein ubiquitination. Predicted to be active in cytoplasm. Orthologous to human WWP1 (WW domain containing E3 ubiquitin protein ligase 1).
RGD Description
Predicted to enable ubiquitin protein ligase activity. Predicted to be involved in negative regulation of DNA-templated transcription; proteasome-mediated ubiquitin-dependent protein catabolic process; and protein ubiquitination. Predicted to be active in cytoplasm. Orthologous to human WWP1 (WW domain containing E3 ubiquitin protein ligase 1); PARTICIPATES IN transforming growth factor-beta Smad dependent signaling pathway; endocytosis pathway; ubiquitin/proteasome degradation pathway; INTERACTS WITH 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine; 2,6-dinitrotoluene.
Cross References
Additional Information
Literature

Orthology

Gene tree
PANTHER:PTHR11254
Links to orthology data in JBrowse by filter level: Stringent,  Moderate,  No filter,  Best and Best Reverse

Paralogy

Function - GO Annotations

Pathways

No data available

Phenotypes

Primary Sources
None
Other Sources
None

Disease Associations

Cases where the expected disease association was NOT found
Cell color indicative of annotation volume

Transgenic Alleles

Models

Sequence Feature Viewer

Genome location
Assembly version
mRatBN7.2
Viewer Help
33.10M33.11M33.12M33.13M33.14M33.15M33.16M33.17M33.18M

Sequence Details

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Expression

Primary Sources
None
Other Sources
Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

Molecular Interactions

Genetic Interactions