Gene

Cpa6

Species
Rattus norvegicus
Symbol
Cpa6
Name
carboxypeptidase A6
Synonyms
  • LOC312913
Biotype
protein coding gene
Automated Description
Predicted to enable metallocarboxypeptidase activity. Predicted to be involved in proteolysis. Predicted to be active in extracellular space. Human ortholog(s) of this gene implicated in familial febrile seizures 11 and familial temporal lobe epilepsy 5. Orthologous to human CPA6 (carboxypeptidase A6).
RGD Description
Predicted to enable metallocarboxypeptidase activity. Predicted to be involved in proteolysis. Predicted to be active in extracellular space. Human ortholog(s) of this gene implicated in familial febrile seizures 11 and familial temporal lobe epilepsy 5. Orthologous to human CPA6 (carboxypeptidase A6); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,3,7,8-Tetrachlorodibenzofuran; acrylamide.
Cross References
Additional Information
Literature

Orthology

Gene tree
PANTHER:PTHR11705
Stringency:
Additional filters to further constrain the results:
Species Gene symbol Count Best Best reverse
Method
Ensembl ComparaHGNCHieranoidInParanoidOMAOrthoFinderOrthoInspectorPANTHERPhylomeDBSonicParanoidXenbaseZFIN
Homo sapiensCPA610 of 10YesYes  
Mus musculusCpa69 of 9YesYes   
Xenopus tropicaliscpa68 of 9YesYes   
Danio reriocpa69 of 9YesYes   
Drosophila melanogasterCG185855 of 9YesNo   
Drosophila melanogasterCG123745 of 9YesNo   
Drosophila melanogasterCG70255 of 9YesNo   
Drosophila melanogasterCG176335 of 9YesNo   
Drosophila melanogasterCG40175 of 9YesNo   
Drosophila melanogasterCG148205 of 9YesNo   
Drosophila melanogasterCG85623 of 9NoYes   
Drosophila melanogasterCG184173 of 9NoYes   
Drosophila melanogasterCG85603 of 9NoYes   
Drosophila melanogasterCG31083 of 9NoYes   
Drosophila melanogasterCG323793 of 9NoYes   
Caenorhabditis elegansT06A4.14 of 9YesNo   
Saccharomyces cerevisiaeECM147 of 9YesNo   
Links to orthology data in JBrowse by filter level: Stringent,  Moderate,  No filter,  Best and Best Reverse

Paralogy

Gene symbolRank Alignment Length (aa) Similarity %Identity %Method Count
Method
Ensembl ComparaHGNCInParanoidOMAOrthoFinderOrthoInspectorPANTHERPhylomeDBSonicParanoidSGD
Cpb1127771527 of 9 
Cpb2229964467 of 9 
Cpa3328366497 of 9 
Cpa2428563467 of 9 
Cpa1528261437 of 9 
Cpa5627862447 of 9 
Cpa4728160437 of 9 

Function - GO Annotations

No function available for that gene

Pathways

No data available

Phenotypes

Primary Sources
None
Other Sources
None
No data available

Disease Associations

Cases where the expected disease association was NOT found
Must provide at least one subject
Cell color indicative of annotation volume
Species
Gene
Association
Disease Qualifier
Disease
Evidence
Source
Based On
References
Homo sapiensCPA6
is implicated infamilial febrile seizures 11
  • IAGP
    Homo sapiensCPA6
    is implicated infamilial temporal lobe epilepsy 5
    • IAGP
      Showing 1 - 2 of 2 rows
      per page

      Alleles and Variants

      Genome location
      Assembly version
      mRatBN7.2
      Viewer Help
      8.55M8.60M8.65M8.70M8.75M8.80M8.85M
      Variant Types and ConsequencesOnly variants associated to alleles are shown in the graphics above. See all variants in JBrowse.
      Allele/Variant Symbol
      Allele Synonyms
      Category
      Variant
      Variant type
      Molecular consequence
      Has Disease Annotations
      Has Phenotype Annotations
      NC_051340.1:g.8558183C>Tvariant
      SNP
      • intron variant
      NC_051340.1:g.8598791G>Avariant
      SNP
      • intron variant
      NC_051340.1:g.8608892A>Gvariant
      SNP
      • intron variant
      NC_051340.1:g.8610365G>Avariant
      SNP
      • intron variant
      NC_051340.1:g.8625743A>Cvariant
      SNP
      • intron variant
      NC_051340.1:g.8562887G>Avariant
      SNP
      • intron variant
      NC_051340.1:g.8628018C>Tvariant
      SNP
      • intron variant
      NC_051340.1:g.8656298C>Tvariant
      SNP
      • intron variant
      NC_051340.1:g.8657739A>Gvariant
      SNP
      • intron variant
      NC_051340.1:g.8662810C>Tvariant
      SNP
      • intron variant
      Showing 1 - 10 of 1,466 rows
      per page

      Transgenic Alleles

      No data available

      Models

      No data available

      Sequence Feature Viewer

      Genome location
      Assembly version
      mRatBN7.2
      Viewer Help
      8.55M8.60M8.65M8.70M8.75M8.80M8.85MENSRNOT00000007491.7 (Cpa6)NM_001415862.1 (Cpa6)

      Sequence Details

      Loading...

      Expression

      Primary Sources
      None
      Other Sources
      Must provide at least one subject
      Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

      Molecular Interactions

      No data available

      Genetic Interactions

      No data available