Predicted to enable ubiquitin protein ligase activity. Predicted to be involved in endosome to lysosome transport; negative regulation of signal transduction; and protein monoubiquitination. Predicted to act upstream of or within several processes, including heart development; protein polyubiquitination; and smoothened signaling pathway. Predicted to be located in endoplasmic reticulum and plasma membrane. Predicted to be part of ubiquitin ligase complex. Predicted to be active in early endosome and nucleus. Orthologous to human MGRN1 (mahogunin ring finger 1).
RGD Description
Predicted to enable ubiquitin protein ligase activity. Predicted to be involved in endosome to lysosome transport; negative regulation of signal transduction; and protein monoubiquitination. Predicted to act upstream of or within several processes, including heart development; protein polyubiquitination; and smoothened signaling pathway. Predicted to be located in endoplasmic reticulum and plasma membrane. Predicted to be part of ubiquitin ligase complex. Predicted to be active in early endosome and nucleus. Orthologous to human MGRN1 (mahogunin ring finger 1); PARTICIPATES IN melanocortin system pathway; ubiquitin/proteasome degradation pathway; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; bisphenol A; cadmium dichloride.