Gene

Chd7

Species
Rattus norvegicus
Symbol
Chd7
Name
chromodomain helicase DNA binding protein 7
Synonyms
  • chromodomain-helicase-DNA-binding protein 7
  • LOC312974
Biotype
protein coding gene
Automated Description
Predicted to enable several functions, including ATP hydrolysis activity; ATP-dependent chromatin remodeler activity; and promoter-specific chromatin binding activity. Predicted to be involved in several processes, including face development; nervous system development; and regulation of growth hormone secretion. Predicted to act upstream of or within several processes, including circulatory system development; embryonic morphogenesis; and nervous system development. Predicted to be located in chromatin; nucleolus; and nucleoplasm. Predicted to be active in nucleus. Human ortholog(s) of this gene implicated in CHARGE syndrome and hypogonadotropic hypogonadism 5 with or without anosmia. Orthologous to human CHD7 (chromodomain helicase DNA binding protein 7).
RGD Description
Predicted to enable several functions, including ATP hydrolysis activity; ATP-dependent chromatin remodeler activity; and promoter-specific chromatin binding activity. Predicted to be involved in several processes, including face development; nervous system development; and regulation of growth hormone secretion. Predicted to act upstream of or within several processes, including circulatory system development; embryonic morphogenesis; and nervous system development. Predicted to be located in chromatin; nucleolus; and nucleoplasm. Predicted to be active in nucleus. Human ortholog(s) of this gene implicated in CHARGE syndrome and hypogonadotropic hypogonadism 5 with or without anosmia. Orthologous to human CHD7 (chromodomain helicase DNA binding protein 7); PARTICIPATES IN Wnt signaling, non-canonical pathway; INTERACTS WITH 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine; 2,6-dinitrotoluene.
Cross References
Additional Information
Literature

Orthology

Gene tree
PANTHER:PTHR46850
Links to orthology data in JBrowse by filter level: Stringent,  Moderate,  No filter,  Best and Best Reverse

Paralogy

Function - GO Annotations

Pathways

No data available

Phenotypes

Primary Sources
None
Other Sources
None

Disease Associations

Cases where the expected disease association was NOT found
Cell color indicative of annotation volume

Transgenic Alleles

Models

Sequence Feature Viewer

Genome location
Assembly version
mRatBN7.2
Viewer Help
21.82M21.84M21.86M21.88M21.90M21.92M21.94M21.96M21.98M

Sequence Details

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Expression

Primary Sources
None
Other Sources
Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

Molecular Interactions

Genetic Interactions