Predicted to enable several functions, including ATP hydrolysis activity; ATP-dependent chromatin remodeler activity; and histone binding activity. Predicted to be involved in chromatin remodeling; microtubule cytoskeleton organization; and negative regulation of transcription by RNA polymerase II. Predicted to act upstream of or within chromatin organization. Predicted to be located in several cellular components, including centriolar satellite; chromatin; and nuclear lumen. Predicted to be part of NuRD complex. Predicted to be active in nucleus. Biomarker of pancreatic carcinoma. Orthologous to human CHD3 (chromodomain helicase DNA binding protein 3).
RGD Description
Predicted to enable several functions, including ATP hydrolysis activity; ATP-dependent chromatin remodeler activity; and histone binding activity. Predicted to be involved in chromatin remodeling; microtubule cytoskeleton organization; and negative regulation of transcription by RNA polymerase II. Predicted to act upstream of or within chromatin organization. Predicted to be located in several cellular components, including centriolar satellite; chromatin; and nuclear lumen. Predicted to be part of NuRD complex. Predicted to be active in nucleus. Biomarker of pancreatic carcinoma. Orthologous to human CHD3 (chromodomain helicase DNA binding protein 3); PARTICIPATES IN CHD family mediated chromatin remodeling pathway; INTERACTS WITH (+)-schisandrin B; 2,3,7,8-tetrachlorodibenzodioxine; amphetamine.