Gene

Chd3

Species
Rattus norvegicus
Symbol
Chd3
Name
chromodomain helicase DNA binding protein 3
Synonyms
  • chromodomain-helicase-DNA-binding protein 3
  • LOC303241
Biotype
protein coding gene
Automated Description
Predicted to enable several functions, including ATP hydrolysis activity; ATP-dependent chromatin remodeler activity; and histone binding activity. Predicted to be involved in chromatin remodeling; microtubule cytoskeleton organization; and negative regulation of transcription by RNA polymerase II. Predicted to act upstream of or within chromatin organization. Predicted to be located in several cellular components, including centriolar satellite; chromatin; and nuclear lumen. Predicted to be part of NuRD complex. Predicted to be active in nucleus. Biomarker of pancreatic carcinoma. Orthologous to human CHD3 (chromodomain helicase DNA binding protein 3).
RGD Description
Predicted to enable several functions, including ATP hydrolysis activity; ATP-dependent chromatin remodeler activity; and histone binding activity. Predicted to be involved in chromatin remodeling; microtubule cytoskeleton organization; and negative regulation of transcription by RNA polymerase II. Predicted to act upstream of or within chromatin organization. Predicted to be located in several cellular components, including centriolar satellite; chromatin; and nuclear lumen. Predicted to be part of NuRD complex. Predicted to be active in nucleus. Biomarker of pancreatic carcinoma. Orthologous to human CHD3 (chromodomain helicase DNA binding protein 3); PARTICIPATES IN CHD family mediated chromatin remodeling pathway; INTERACTS WITH (+)-schisandrin B; 2,3,7,8-tetrachlorodibenzodioxine; amphetamine.
Cross References
Additional Information
Literature

Orthology

Gene tree
PANTHER:PTHR45623
Links to orthology data in JBrowse by filter level: Stringent,  Moderate,  No filter,  Best and Best Reverse

Paralogy

Function - GO Annotations

Pathways

No data available

Phenotypes

Primary Sources
None
Other Sources
None

Disease Associations

Cases where the expected disease association was NOT found
Cell color indicative of annotation volume

Transgenic Alleles

Models

Sequence Feature Viewer

Genome location
Assembly version
mRatBN7.2
Viewer Help
54.065M54.070M54.075M54.080M54.085M54.090M

Sequence Details

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Expression

Primary Sources
None
Other Sources
Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

Molecular Interactions

Genetic Interactions