Predicted to enable endopeptidase activator activity and enzyme binding activity. Predicted to be involved in several processes, including amyloid-beta formation; positive regulation of endopeptidase activity; and proteolysis. Is active in presynaptic membrane. Human ortholog(s) of this gene implicated in hidradenitis suppurativa. Orthologous to human PSENEN (presenilin enhancer, gamma-secretase subunit).
RGD Description
Predicted to enable endopeptidase activator activity and enzyme binding activity. Predicted to be involved in several processes, including amyloid-beta formation; membrane protein proteolysis; and positive regulation of endopeptidase activity. Is active in presynaptic membrane. Human ortholog(s) of this gene implicated in hidradenitis suppurativa. Orthologous to human PSENEN (presenilin enhancer, gamma-secretase subunit); PARTICIPATES IN Notch signaling pathway; syndecan signaling pathway; Alzheimer's disease pathway; INTERACTS WITH (+)-schisandrin B; acetamide; bisphenol A.