Gene

Txndc2

Species
Rattus norvegicus
Symbol
Txndc2
Name
thioredoxin domain containing 2
Synonyms
  • MGC94320
  • similar to spermatid-specific thioredoxin
Biotype
protein coding gene
Automated Description
Predicted to enable protein disulfide isomerase activity and thioredoxin-disulfide reductase (NADPH) activity. Predicted to be involved in cell differentiation; cellular oxidant detoxification; and spermatogenesis. Predicted to act upstream of or within cellular response to reactive oxygen species and flagellated sperm motility. Located in outer dense fiber. Orthologous to human TXNDC2 (thioredoxin domain containing 2).
RGD Description
Predicted to enable protein disulfide isomerase activity and thioredoxin-disulfide reductase (NADPH) activity. Predicted to be involved in cell differentiation; cellular oxidant detoxification; and spermatogenesis. Predicted to act upstream of or within cellular response to reactive oxygen species and flagellated sperm motility. Located in outer dense fiber. Orthologous to human TXNDC2 (thioredoxin domain containing 2); INTERACTS WITH bisphenol A; 1,2-dichloroethane (ortholog); 4,4'-diaminodiphenylmethane (ortholog).
Cross References
Additional Information
Literature

Orthology

Gene tree
PANTHER:PTHR10438
Links to orthology data in JBrowse by filter level: Stringent,  Moderate,  No filter,  Best and Best Reverse

Paralogy

Function - GO Annotations

Pathways

No data available

Phenotypes

Primary Sources
None
Other Sources
None

Disease Associations

Cases where the expected disease association was NOT found
Cell color indicative of annotation volume

Transgenic Alleles

Models

Sequence Feature Viewer

Genome location
Assembly version
mRatBN7.2
Viewer Help
105.2310M105.2315M105.2320M105.2325M105.2330M105.2335M105.2340M105.2345M105.2350M

Sequence Details

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Expression

Primary Sources
None
Other Sources
Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

Molecular Interactions

Genetic Interactions