Gene

Crppa

Species
Rattus norvegicus
Symbol
Crppa
Name
CDP-L-ribitol pyrophosphorylase A
Synonyms
  • 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase-like protein
  • D-ribitol-5-phosphate cytidylyltransferase
Biotype
protein coding gene
Automated Description
Predicted to enable D-ribitol-5-phosphate cytidylyltransferase activity and protein homodimerization activity. Predicted to be involved in protein O-linked mannosylation. Predicted to act upstream of or within axon guidance and protein glycosylation. Predicted to be active in cytosol. Human ortholog(s) of this gene implicated in autosomal recessive limb-girdle muscular dystrophy type 2U and congenital muscular dystrophy-dystroglycanopathy A7. Orthologous to human CRPPA (CDP-L-ribitol pyrophosphorylase A).
RGD Description
Predicted to enable D-ribitol-5-phosphate cytidylyltransferase activity and protein homodimerization activity. Predicted to be involved in protein O-linked mannosylation. Predicted to act upstream of or within axon guidance and protein glycosylation. Predicted to be active in cytosol. Human ortholog(s) of this gene implicated in autosomal recessive limb-girdle muscular dystrophy type 2U and congenital muscular dystrophy-dystroglycanopathy A7. Orthologous to human CRPPA (CDP-L-ribitol pyrophosphorylase A); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; aconitine; bisphenol A.
Cross References
Additional Information
Literature

Orthology

Gene tree
PANTHER:PTHR43015
Links to orthology data in JBrowse by filter level: Stringent,  Moderate,  No filter,  Best and Best Reverse

Paralogy

Function - GO Annotations

Pathways

No data available

Phenotypes

Primary Sources
None
Other Sources
None

Disease Associations

Cases where the expected disease association was NOT found
Cell color indicative of annotation volume

Transgenic Alleles

Models

Sequence Feature Viewer

Genome location
Assembly version
mRatBN7.2
Viewer Help
53.15M53.20M53.25M53.30M53.35M

Sequence Details

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Expression

Primary Sources
None
Other Sources
Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

Molecular Interactions

Genetic Interactions