Predicted to enable several functions, including F-box domain binding activity; beta-catenin binding activity; and cullin family protein binding activity. Predicted to be involved in several processes, including SCF-dependent proteasomal ubiquitin-dependent protein catabolic process; maintenance of protein location in nucleus; and positive regulation of ubiquitin protein ligase activity. Predicted to act upstream of or within protein K48-linked ubiquitination and protein monoubiquitination. Located in gap junction. Orthologous to human SKP1 (S-phase kinase associated protein 1).
RGD Description
Predicted to enable several functions, including F-box domain binding activity; beta-catenin binding activity; and cullin family protein binding activity. Predicted to be involved in several processes, including SCF-dependent proteasomal ubiquitin-dependent protein catabolic process; maintenance of protein location in nucleus; and positive regulation of ubiquitin protein ligase activity. Predicted to act upstream of or within protein K48-linked ubiquitination and protein monoubiquitination. Located in gap junction. Orthologous to human SKP1 (S-phase kinase associated protein 1); PARTICIPATES IN Notch signaling pathway; nuclear factor kappa B signaling pathway; nuclear factor, erythroid 2 like 2 signaling pathway; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; acrylamide; Brodifacoum.