Predicted to enable sequence-specific double-stranded DNA binding activity. Predicted to be involved in negative regulation of transcription by RNA polymerase II. Predicted to act upstream of or within several processes, including nodal signaling pathway; positive regulation of amacrine cell differentiation; and regulation of gastrulation. Predicted to be located in centrosome and nucleoplasm. Orthologous to human TGIF2 (TGFB induced factor homeobox 2).
RGD Description
Predicted to enable DNA-binding transcription repressor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in negative regulation of transcription by RNA polymerase II. Predicted to act upstream of or within several processes, including nodal signaling pathway; positive regulation of amacrine cell differentiation; and regulation of gastrulation. Predicted to be located in centrosome and nucleoplasm. Predicted to be active in nucleus. Orthologous to human TGIF2 (TGFB induced factor homeobox 2); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 6-propyl-2-thiouracil; acrylamide.