Gene

Tgif2

Species
Rattus norvegicus
Symbol
Tgif2
Name
TGFB-induced factor homeobox 2
Synonyms
  • homeobox protein TGIF2
  • LOC499929
Biotype
protein coding gene
Automated Description
Predicted to enable sequence-specific double-stranded DNA binding activity. Predicted to be involved in negative regulation of transcription by RNA polymerase II. Predicted to act upstream of or within several processes, including nodal signaling pathway; positive regulation of amacrine cell differentiation; and regulation of gastrulation. Predicted to be located in centrosome and nucleoplasm. Orthologous to human TGIF2 (TGFB induced factor homeobox 2).
RGD Description
Predicted to enable DNA-binding transcription repressor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in negative regulation of transcription by RNA polymerase II. Predicted to act upstream of or within several processes, including nodal signaling pathway; positive regulation of amacrine cell differentiation; and regulation of gastrulation. Predicted to be located in centrosome and nucleoplasm. Predicted to be active in nucleus. Orthologous to human TGIF2 (TGFB induced factor homeobox 2); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 6-propyl-2-thiouracil; acrylamide.
Cross References
Additional Information
Literature

Orthology

Gene tree
PANTHER:PTHR11850
Links to orthology data in JBrowse by filter level: Stringent,  Moderate,  No filter,  Best and Best Reverse

Paralogy

Function - GO Annotations

Pathways

No data available

Phenotypes

Primary Sources
None
Other Sources
None

Disease Associations

Cases where the expected disease association was NOT found
Cell color indicative of annotation volume

Transgenic Alleles

Models

Sequence Feature Viewer

Genome location
Assembly version
mRatBN7.2
Viewer Help
145.334M145.336M145.338M145.340M145.342M145.344M145.346M145.348M

Sequence Details

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Expression

Primary Sources
None
Other Sources
Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

Molecular Interactions

Genetic Interactions