Version: 8.0.0Date: Tue Jan 28 2025
Gene
Fmnl2
- Species
- Rattus norvegicus
- Symbol
- Fmnl2
- Name
- formin-like 2
- Synonyms
- formin-like protein 2
- LOC499797
- Biotype
- protein coding gene
- Automated Description
- Predicted to enable actin filament binding activity. Predicted to be involved in cell migration; cortical actin cytoskeleton organization; and regulation of cell shape. Is active in glutamatergic synapse and postsynapse. Orthologous to human FMNL2 (formin like 2).
- RGD Description
- Predicted to enable actin filament binding activity. Predicted to be involved in cell migration; cortical actin cytoskeleton organization; and regulation of cell shape. Is active in glutamatergic synapse and postsynapse. Orthologous to human FMNL2 (formin like 2); INTERACTS WITH 1-naphthyl isothiocyanate; 2,3,7,8-tetrachlorodibenzodioxine; 4,4'-diaminodiphenylmethane.
- Cross References
- Additional Information
- Literature
Orthology
- Gene tree
- PANTHER:PTHR45857
Links to orthology data in JBrowse by filter level: Stringent, Moderate, No filter, Best and Best Reverse
Paralogy
| Gene symbol | Rank | Alignment Length (aa) | Similarity % | Identity % | Method Count | Method Ensembl ComparaHGNCInParanoidOMAOrthoFinderOrthoInspectorPANTHERPhylomeDBSonicParanoidSGD |
|---|---|---|---|---|---|---|
| Fmnl3 | 1 | 1078 | 80 | 68 | 7 of 9 | ☑☐☑☐☑☑☑☑☑ |
| Fmnl1 | 2 | 1119 | 73 | 59 | 7 of 9 | ☑☐☑☐☑☑☑☑☑ |
| Daam2 | 3 | 1222 | 45 | 26 | 5 of 9 | ☑☐☑☐☑☑☐☑☐ |
| Daam1 | 4 | 1208 | 43 | 26 | 5 of 9 | ☑☐☑☐☑☑☐☑☐ |
| Diaph1 | 5 | 1244 | 41 | 23 | 3 of 9 | ☑☐☐☐☑☐☐☑☐ |
| Diaph3 | 6 | 1143 | 41 | 26 | 4 of 9 | ☑☐☐☐☑☑☐☑☐ |
| Inf2 | 7 | 1202 | 40 | 24 | 2 of 9 | ☐☐☑☐☐☐☐☑☐ |
| Diaph2 | 8 | 1193 | 41 | 24 | 2 of 9 | ☐☐☐☐☑☐☐☑☐ |
| Fhod1 | 9 | 1163 | 35 | 20 | 2 of 9 | ☑☐☐☐☐☐☐☑☐ |
| Fhod3 | 10 | 1120 | 36 | 20 | 2 of 9 | ☑☐☐☐☐☐☐☑☐ |
| Fhdc1 | 11 | 598 | 42 | 25 | 2 of 9 | ☑☐☐☐☐☐☐☑☐ |
| Grid2ip | 12 | 516 | 41 | 24 | 2 of 9 | ☑☐☐☐☐☐☐☑☐ |
Phenotypes
- Primary Sources
- None
- Other Sources
- None
Phenotype Term | Annotation details | References |
|---|---|---|
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Disease Associations
Cases where the expected disease association was NOT found
Must provide at least one subject
Cell color indicative of annotation volume
No data available
Alleles and Variants
Allele/Variant Symbol | Allele Synonyms | Category | Variant | Variant type | Molecular consequence | Has Disease Annotations | Has Phenotype Annotations |
|---|---|---|---|---|---|---|---|
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Transgenic Alleles
Species (carrying the transgene) | Allele symbol | Transgenic construct | Expressed components | Knock-down targets | Regulatory regions | Has Disease Annotations | Has Phenotype Annotations |
|---|---|---|---|---|---|---|---|
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Models
Model name | Experimental condition | Associated Human Diseases | Associated Phenotypes | Modifier | Source |
|---|---|---|---|---|---|
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Sequence Feature Viewer
- Genome location
- Chr3:37348574...37624754 + (276.18 kb)
- Assembly version
- mRatBN7.2
- Viewer Help
Data currently unavailable; sequence viewer under construction
Expression
- Primary Sources
- None
- Other Sources
Must provide at least one subject
Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.