Gene

Epha4

Species
Rattus norvegicus
Symbol
Epha4
Name
Eph receptor A4
Synonyms
  • ephrin type-A receptor 4
  • LOC316539
Biotype
protein coding gene
Automated Description
Enables ephrin receptor binding activity. Involved in glial cell migration; regulation of neuron projection development; and regulation of synapse organization. Located in several cellular components, including dendrite; distal axon; and perikaryon. Is active in glutamatergic synapse. Biomarker of toxic encephalopathy. Orthologous to human EPHA4 (EPH receptor A4).
RGD Description
Enables ephrin receptor binding activity. Involved in glial cell migration; regulation of neuron projection development; and regulation of synapse organization. Located in several cellular components, including dendrite; distal axon; and perikaryon. Is active in glutamatergic synapse. Biomarker of toxic encephalopathy. Orthologous to human EPHA4 (EPH receptor A4); PARTICIPATES IN ephrin - ephrin receptor bidirectional signaling axis; INTERACTS WITH 1,3-dinitrobenzene; 17alpha-ethynylestradiol; 3,4-methylenedioxymethamphetamine.
Cross References
Additional Information
Literature

Orthology

Gene tree
PANTHER:PTHR46877
Links to orthology data in JBrowse by filter level: Stringent,  Moderate,  No filter,  Best and Best Reverse

Paralogy

Function - GO Annotations

Pathways

No data available

Phenotypes

Primary Sources
None
Other Sources
None

Disease Associations

Cases where the expected disease association was NOT found
Cell color indicative of annotation volume

Transgenic Alleles

Models

Sequence Feature Viewer

Genome location
Assembly version
mRatBN7.2
Viewer Help
78.82M78.84M78.86M78.88M78.90M78.92M78.94M

Sequence Details

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Expression

Primary Sources
None
Other Sources
Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

Molecular Interactions

Genetic Interactions