Predicted to enable enzyme binding activity and enzyme inhibitor activity. Predicted to be involved in negative regulation of metabolic process. Predicted to act upstream of or within several processes, including GDP-mannose biosynthetic process; motor behavior; and protein glycosylation. Predicted to be part of GDP-mannose pyrophosphorylase complex. Predicted to be active in cytoplasm. Human ortholog(s) of this gene implicated in alacrima, achalasia, and impaired intellectual development syndrome. Orthologous to human GMPPA (GDP-mannose pyrophosphorylase A).
RGD Description
Predicted to enable enzyme binding activity and enzyme inhibitor activity. Predicted to be involved in several processes, including negative regulation of nucleobase-containing compound metabolic process; negative regulation of phosphorus metabolic process; and negative regulation of small molecule metabolic process. Predicted to act upstream of or within several processes, including GDP-mannose biosynthetic process; motor behavior; and protein glycosylation. Predicted to be part of GDP-mannose pyrophosphorylase complex. Predicted to be active in cytoplasm. Human ortholog(s) of this gene implicated in alacrima, achalasia, and impaired intellectual development syndrome. Orthologous to human GMPPA (GDP-mannose pyrophosphorylase A); PARTICIPATES IN amino sugar metabolic pathway; fructose and mannose metabolic pathway; nucleotide sugar metabolic pathway; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,6-dinitrotoluene; 6-propyl-2-thiouracil.