Version: 8.0.0
Date: Tue Jan 28 2025
Tnfrsf13c
Rattus norvegicusRGD:1560810
SummaryOrthologyParalogyFunction - GO AnnotationsPathwaysPhenotypesDisease AssociationsAlleles and VariantsTransgenic AllelesModelsSequence Feature ViewerSequence DetailsExpressionMolecular InteractionsGenetic Interactions
Gene

Tnfrsf13c

Species
Rattus norvegicus
Symbol
Tnfrsf13c
Name
TNF receptor superfamily member 13C
Synonyms
  • LOC500910
  • RGD1560810
Biotype
protein coding gene
Automated Description
Predicted to enable signaling receptor activity. Predicted to be involved in positive regulation of lymphocyte activation. Predicted to act upstream of or within B cell homeostasis; positive regulation of germinal center formation; and positive regulation of type II interferon production. Predicted to be active in external side of plasma membrane. Human ortholog(s) of this gene implicated in common variable immunodeficiency 4. Orthologous to human TNFRSF13C (TNF receptor superfamily member 13C).
RGD Description
Predicted to enable signaling receptor activity. Predicted to be involved in positive regulation of lymphocyte activation. Predicted to act upstream of or within B cell homeostasis; positive regulation of germinal center formation; and positive regulation of type II interferon production. Predicted to be active in external side of plasma membrane. Human ortholog(s) of this gene implicated in common variable immunodeficiency 4. Orthologous to human TNFRSF13C (TNF receptor superfamily member 13C); PARTICIPATES IN cytokine mediated signaling pathway; primary immunodeficiency pathway; INTERACTS WITH 1,2-dimethylhydrazine; 17beta-estradiol; alpha-Zearalanol.
Cross References
Additional Information
Literature

Orthology

Gene tree
PANTHER:PTHR20437
No data available
Links to orthology data in JBrowse by filter level: Stringent,  Moderate,  No filter,  Best and Best Reverse

Paralogy

Function - GO Annotations

Pathways

No data available

Phenotypes

Primary Sources
None
Other Sources
None
Phenotype Term
Annotation details
References
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    Disease Associations

    Cases where the expected disease association was NOT found
    Cell color indicative of annotation volume
    Gene
    Association
    Disease Qualifier
    Disease
    Evidence
    Source
    Based On
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      Alleles and Variants

      Allele/Variant Symbol
      Allele Synonyms
      Category
      Variant
      Variant type
      Molecular consequence
      Has Disease Annotations
      Has Phenotype Annotations
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        Transgenic Alleles

        Species
        (carrying the transgene)
        Allele symbol
        Transgenic construct
        Expressed components
        Knock-down targets
        Regulatory regions
        Has Disease Annotations
        Has Phenotype Annotations
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          Models

          Model name
          Experimental condition
          Associated Human Diseases
          Associated Phenotypes
          Modifier
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            Sequence Feature Viewer

            Genome location
            Assembly version
            mRatBN7.2
            Viewer Help
            113.7362M113.7364M113.7366M113.7368M113.7370M113.7372M113.7374M113.7376M113.7378M113.7380M113.7382M113.7384M

            Sequence Details

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            Expression

            Primary Sources
            None
            Other Sources
            Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

            Molecular Interactions

            Tnfrsf13c molecule type
            Interactor gene
            Interactor species
            Interactor molecule type
            Detection methods
            Source
            Reference
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              Genetic Interactions

              Tnfrsf13c role
              Tnfrsf13c genetic perturbation
              Interactor gene
              Interactor species
              Interactor role
              Interactor genetic perturbation
              Interaction type
              Phenotype or trait
              Source
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