Gene

Ptprd

Species
Rattus norvegicus
Symbol
Ptprd
Name
protein tyrosine phosphatase, receptor type, D
Synonyms
  • LOC103692382
  • LOC313278
Biotype
protein coding gene
Automated Description
Predicted to enable cell adhesion molecule binding activity; protein tyrosine phosphatase activity; and signaling receptor binding activity. Involved in several processes, including cellular response to platelet-derived growth factor stimulus; regulation of postsynaptic density assembly; and synaptic membrane adhesion. Is active in glutamatergic synapse. Biomarker of restless legs syndrome. Human ortholog(s) of this gene implicated in coronary artery disease; diabetes mellitus; hypertension; and type 2 diabetes mellitus. Orthologous to human PTPRD (protein tyrosine phosphatase receptor type D).
RGD Description
Predicted to enable cell adhesion molecule binding activity; protein tyrosine phosphatase activity; and signaling receptor binding activity. Involved in several processes, including cellular response to platelet-derived growth factor stimulus; regulation of postsynaptic density assembly; and synaptic membrane adhesion. Is active in glutamatergic synapse. Biomarker of restless legs syndrome. Human ortholog(s) of this gene implicated in coronary artery disease; diabetes mellitus; hypertension; and type 2 diabetes mellitus. Orthologous to human PTPRD (protein tyrosine phosphatase receptor type D); INTERACTS WITH (+)-schisandrin B; 1-naphthyl isothiocyanate; 17alpha-ethynylestradiol.
Cross References
Additional Information
Literature

Orthology

Gene tree
PANTHER:PTHR44170
Links to orthology data in JBrowse by filter level: Stringent,  Moderate,  No filter,  Best and Best Reverse

Paralogy

Function - GO Annotations

Pathways

No data available

Phenotypes

Primary Sources
None
Other Sources
None

Disease Associations

Cases where the expected disease association was NOT found
Cell color indicative of annotation volume

Transgenic Alleles

Models

Sequence Feature Viewer

Genome location
Assembly version
mRatBN7.2
Viewer Help
90.1M90.2M90.3M90.4M90.5M90.6M

Sequence Details

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Expression

Primary Sources
None
Other Sources
Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

Molecular Interactions

Genetic Interactions