Gene

Zfyve19

Species
Rattus norvegicus
Symbol
Zfyve19
Name
zinc finger FYVE-type containing 19
Synonyms
  • abscission/NoCut checkpoint regulator
  • LOC499871
Biotype
protein coding gene
Automated Description
Predicted to enable phosphatidylinositol-3-phosphate binding activity. Predicted to be involved in abscission; midbody abscission; and negative regulation of cell cycle process. Predicted to be active in centrosome; cleavage furrow; and midbody. Human ortholog(s) of this gene implicated in progressive familial intrahepatic cholestasis. Orthologous to human ZFYVE19 (zinc finger FYVE-type containing 19).
RGD Description
Predicted to enable phosphatidylinositol-3-phosphate binding activity. Predicted to be involved in abscission; mitotic cytokinesis checkpoint signaling; and negative regulation of cytokinesis. Predicted to be active in centrosome; cleavage furrow; and midbody. Human ortholog(s) of this gene implicated in progressive familial intrahepatic cholestasis. Orthologous to human ZFYVE19 (zinc finger FYVE-type containing 19); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; bisphenol A; gentamycin.
Cross References
Additional Information
Literature

Orthology

Gene tree
PANTHER:PTHR46603
Links to orthology data in JBrowse by filter level: Stringent,  Moderate,  No filter,  Best and Best Reverse

Paralogy

Function - GO Annotations

Pathways

No data available

Phenotypes

Primary Sources
None
Other Sources
None

Disease Associations

Cases where the expected disease association was NOT found
Cell color indicative of annotation volume

Transgenic Alleles

Models

Sequence Feature Viewer

Genome location
Assembly version
mRatBN7.2
Viewer Help
106.196M106.197M106.198M106.199M106.200M106.201M106.202M106.203M

Sequence Details

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Expression

Primary Sources
None
Other Sources
Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

Molecular Interactions

Genetic Interactions