Gene

Usp10

Species
Rattus norvegicus
Symbol
Usp10
Name
ubiquitin specific peptidase 10
Synonyms
  • deubiquitinating enzyme 10
  • MGC124997
Biotype
protein coding gene
Automated Description
Predicted to enable several functions, including cysteine-type peptidase activity; p53 binding activity; and transmembrane transporter binding activity. Predicted to be involved in several processes, including monoubiquitinated protein deubiquitination; negative regulation of canonical NF-kappaB signal transduction; and negative regulation of stress granule assembly. Predicted to be located in cytoplasm; intermediate filament cytoskeleton; and nucleoplasm. Predicted to be part of protein-containing complex. Predicted to be active in cytosolic ribosome; early endosome; and nucleus. Orthologous to human USP10 (ubiquitin specific peptidase 10).
RGD Description
Predicted to enable several functions, including cysteine-type peptidase activity; p53 binding activity; and transmembrane transporter binding activity. Predicted to be involved in several processes, including monoubiquitinated protein deubiquitination; negative regulation of canonical NF-kappaB signal transduction; and negative regulation of stress granule assembly. Predicted to be located in cytoplasm; intermediate filament cytoskeleton; and nucleoplasm. Predicted to be part of protein-containing complex. Predicted to be active in cytosolic ribosome; early endosome; and nucleus. Orthologous to human USP10 (ubiquitin specific peptidase 10); INTERACTS WITH (+)-schisandrin B; 2,4-dinitrotoluene; 2,6-dinitrotoluene.
Cross References
Additional Information
Literature

Orthology

Gene tree
PANTHER:PTHR24006
Links to orthology data in JBrowse by filter level: Stringent,  Moderate,  No filter,  Best and Best Reverse

Paralogy

Function - GO Annotations

Pathways

No data available

Phenotypes

Primary Sources
None
Other Sources
None

Disease Associations

Cases where the expected disease association was NOT found
Cell color indicative of annotation volume

Transgenic Alleles

Models

Sequence Feature Viewer

Genome location
Assembly version
mRatBN7.2
Viewer Help
47.975M47.980M47.985M47.990M47.995M48.000M48.005M48.010M

Sequence Details

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Expression

Primary Sources
None
Other Sources
Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

Molecular Interactions

Genetic Interactions