Predicted to enable several functions, including heat shock protein binding activity; histone deacetylase binding activity; and transcription corepressor activity. Predicted to contribute to ubiquitin-protein transferase activity. Predicted to be involved in several processes, including negative regulation of biomineral tissue development; negative regulation of transcription by RNA polymerase II; and specification of axis polarity. Predicted to act upstream of or within blastocyst hatching. Predicted to be located in nucleoplasm. Predicted to be part of BCOR complex. Predicted to be active in nucleus. Human ortholog(s) of this gene implicated in dental caries; eye disease (multiple); and gastrointestinal system cancer (multiple). Orthologous to several human genes including BCOR (BCL6 corepressor).
RGD Description
Predicted to enable several functions, including heat shock protein binding activity; histone deacetylase binding activity; and transcription corepressor activity. Predicted to contribute to ubiquitin-protein transferase activity. Predicted to be involved in several processes, including negative regulation of biomineral tissue development; negative regulation of transcription by RNA polymerase II; and specification of axis polarity. Predicted to act upstream of or within blastocyst hatching. Predicted to be located in nucleoplasm. Predicted to be part of BCOR complex. Predicted to be active in nucleus. Human ortholog(s) of this gene implicated in dental caries; eye disease (multiple); and gastrointestinal system cancer (multiple). Orthologous to several human genes including BCOR (BCL6 corepressor); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; bisphenol A; gentamycin.