Gene

Bcor

Species
Rattus norvegicus
Symbol
Bcor
Name
BCL6 co-repressor
Synonyms
  • BCL-6 corepressor
  • Bcl6 interacting corepressor
Biotype
protein coding gene
Automated Description
Predicted to enable several functions, including heat shock protein binding activity; histone deacetylase binding activity; and transcription corepressor activity. Predicted to contribute to ubiquitin-protein transferase activity. Predicted to be involved in several processes, including negative regulation of biomineral tissue development; negative regulation of transcription by RNA polymerase II; and specification of axis polarity. Predicted to act upstream of or within blastocyst hatching. Predicted to be located in nucleoplasm. Predicted to be part of BCOR complex. Predicted to be active in nucleus. Human ortholog(s) of this gene implicated in dental caries; eye disease (multiple); and gastrointestinal system cancer (multiple). Orthologous to several human genes including BCOR (BCL6 corepressor).
RGD Description
Predicted to enable several functions, including heat shock protein binding activity; histone deacetylase binding activity; and transcription corepressor activity. Predicted to contribute to ubiquitin-protein transferase activity. Predicted to be involved in several processes, including negative regulation of biomineral tissue development; negative regulation of transcription by RNA polymerase II; and specification of axis polarity. Predicted to act upstream of or within blastocyst hatching. Predicted to be located in nucleoplasm. Predicted to be part of BCOR complex. Predicted to be active in nucleus. Human ortholog(s) of this gene implicated in dental caries; eye disease (multiple); and gastrointestinal system cancer (multiple). Orthologous to several human genes including BCOR (BCL6 corepressor); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; bisphenol A; gentamycin.
Cross References
Additional Information
Literature

Orthology

Gene tree
PANTHER:PTHR24117
Links to orthology data in JBrowse by filter level: Stringent,  Moderate,  No filter,  Best and Best Reverse

Paralogy

Function - GO Annotations

Pathways

No data available

Phenotypes

Primary Sources
None
Other Sources
None

Disease Associations

Cases where the expected disease association was NOT found
Cell color indicative of annotation volume

Transgenic Alleles

Models

Sequence Feature Viewer

Genome location
Assembly version
mRatBN7.2
Viewer Help
10.62M10.64M10.66M10.68M10.70M10.72M

Sequence Details

Loading...

Expression

Primary Sources
None
Other Sources
Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

Molecular Interactions

Genetic Interactions