Gene

Kdm1a

Species
Rattus norvegicus
Symbol
Kdm1a
Name
lysine demethylase 1A
Synonyms
  • amine oxidase (flavin containing) domain 2
  • Aof2
Biotype
protein coding gene
Automated Description
Enables chromatin binding activity. Involved in several processes, including cellular response to cAMP; nervous system development; and positive regulation of cell size. Located in chromatin. Biomarker of breast cancer; diabetic retinopathy; schizophrenia; and transient cerebral ischemia. Orthologous to human KDM1A (lysine demethylase 1A).
RGD Description
Enables chromatin binding activity. Involved in several processes, including cellular response to cAMP; nervous system development; and positive regulation of cell size. Located in chromatin. Biomarker of breast cancer; diabetic retinopathy; schizophrenia; and transient cerebral ischemia. Orthologous to human KDM1A (lysine demethylase 1A); PARTICIPATES IN histone modification pathway; Notch signaling pathway; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; aldehydo-D-glucose; bisphenol A.
Cross References
Additional Information
Literature

Orthology

Gene tree
PANTHER:PTHR10742
Links to orthology data in JBrowse by filter level: Stringent,  Moderate,  No filter,  Best and Best Reverse

Paralogy

Function - GO Annotations

Pathways

No data available

Phenotypes

Primary Sources
None
Other Sources
None

Disease Associations

Cases where the expected disease association was NOT found
Cell color indicative of annotation volume

Transgenic Alleles

Models

Sequence Feature Viewer

Genome location
Assembly version
mRatBN7.2
Viewer Help
148.785M148.790M148.795M148.800M148.805M148.810M148.815M148.820M148.825M148.830M148.835M

Sequence Details

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Expression

Primary Sources
None
Other Sources
Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

Molecular Interactions

Genetic Interactions