Predicted to enable tubulin binding activity and tubulin-glutamic acid ligase activity. Predicted to be involved in sperm axoneme assembly. Predicted to act upstream of or within several processes, including flagellated sperm motility; protein polyglutamylation; and retina development in camera-type eye. Predicted to be located in several cellular components, including 9+0 non-motile cilium; centrosome; and cytosol. Predicted to be active in ciliary basal body. Human ortholog(s) of this gene implicated in cone-rod dystrophy 19. Orthologous to human TTLL5 (tubulin tyrosine ligase like 5).
RGD Description
Predicted to enable tubulin binding activity and tubulin-glutamic acid ligase activity. Predicted to be involved in sperm axoneme assembly. Predicted to act upstream of or within several processes, including flagellated sperm motility; protein polyglutamylation; and retina development in camera-type eye. Predicted to be located in several cellular components, including 9+0 non-motile cilium; centrosome; and cytosol. Predicted to be active in ciliary basal body. Human ortholog(s) of this gene implicated in cone-rod dystrophy 19. Orthologous to human TTLL5 (tubulin tyrosine ligase like 5); INTERACTS WITH Cuprizon; endosulfan; methoxychlor.