Gene

Prss56

Species
Rattus norvegicus
Symbol
Prss56
Name
serine protease 56
Synonyms
  • hypothetical protein LOC363274
  • LOC363274
Biotype
protein coding gene
Automated Description
Predicted to enable serine-type endopeptidase activity. Predicted to be involved in blood coagulation and proteolysis. Predicted to act upstream of or within camera-type eye development. Predicted to be located in endoplasmic reticulum. Predicted to be active in extracellular space. Human ortholog(s) of this gene implicated in isolated microphthalmia 6. Orthologous to human PRSS56 (serine protease 56).
RGD Description
Predicted to enable serine-type endopeptidase activity. Predicted to be involved in blood coagulation; positive regulation of leukocyte chemotaxis; and proteolysis. Predicted to act upstream of or within camera-type eye development. Predicted to be located in endoplasmic reticulum. Predicted to be active in extracellular space. Human ortholog(s) of this gene implicated in isolated microphthalmia 6. Orthologous to human PRSS56 (serine protease 56); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,3,7,8-Tetrachlorodibenzofuran; atrazine.
Cross References
Additional Information
Literature

Orthology

Gene tree
PANTHER:PTHR24252
Stringency:
Additional filters to further constrain the results:
Species Gene symbol Count Best Best reverse
Method
Ensembl ComparaHGNCHieranoidInParanoidOMAOrthoFinderOrthoInspectorPANTHERPhylomeDBSonicParanoidXenbaseZFIN
Homo sapiensPRSS5610 of 10YesYes  
Mus musculusPrss569 of 9YesYes   
Xenopus tropicalisprss566 of 9YesYes   
Danio rerioprss563 of 9YesYes   
Drosophila melanogasterCG334582 of 9YesYes   
Drosophila melanogasterCG334592 of 9YesYes   
Links to orthology data in JBrowse by filter level: Stringent,  Moderate,  No filter,  Best and Best Reverse

Paralogy

Gene symbolRank Alignment Length (aa) Similarity %Identity %Method Count
Method
Ensembl ComparaHGNCInParanoidOMAOrthoFinderOrthoInspectorPANTHERPhylomeDBSonicParanoidSGD
Tmprss6130950392 of 9 
F10231845303 of 9 
St14326057392 of 9 
Tmprss13431346342 of 9 
F7527049373 of 9 
Tmprss11d625255392 of 9 
Cela2a726651372 of 9 
F9831743302 of 9 
Proc927245322 of 9 
Cela11025251332 of 9 
Proz1117644252 of 9 
Tmprss11b122 of 9 
Tmprss11f122 of 9 
Tmprss7122 of 9 
Acr122 of 9 
Tmprss4122 of 9 
Ctrc122 of 9 

Function - GO Annotations

No function available for that gene

Pathways

No data available

Phenotypes

Primary Sources
None
Other Sources
None
No data available

Disease Associations

Cases where the expected disease association was NOT found
Must provide at least one subject
Cell color indicative of annotation volume

Alleles and Variants

Genome location
Assembly version
mRatBN7.2
Viewer Help
87.844M87.846M87.848M87.850M87.852M87.854M87.856M87.858M
Variant Types and ConsequencesOnly variants associated to alleles are shown in the graphics above. See all variants in JBrowse.
Allele/Variant Symbol
Allele Synonyms
Category
Variant
Variant type
Molecular consequence
Has Disease Annotations
Has Phenotype Annotations
NC_051344.1:g.87857232G>Avariant
SNP
  • intron variant
NC_051344.1:g.87852284C>Avariant
SNP
  • 5 prime UTR variant
NC_051344.1:g.87855003G>Tvariant
SNP
  • intron variant
NC_051344.1:g.87856620G>Avariant
SNP
  • intron variant
NC_051344.1:g.87859917T>Cvariant
SNP
  • 3 prime UTR variant
NC_051344.1:g.87844144G>Avariant
SNP
  • intron variant
NC_051344.1:g.87845269T>Cvariant
SNP
  • intron variant
NC_051344.1:g.87846463C>Tvariant
SNP
  • intron variant
NC_051344.1:g.87846970C>Tvariant
SNP
  • intron variant
NC_051344.1:g.87848061C>Gvariant
SNP
  • intron variant
Showing 1 - 10 of 66 rows
per page

Transgenic Alleles

No data available

Models

No data available

Sequence Feature Viewer

Genome location
Assembly version
mRatBN7.2
Viewer Help
87.844M87.846M87.848M87.850M87.852M87.854M87.856M87.858MENSRNOT00000065805.3 (Prss56)ENSRNOT00000095059.1 (Prss56)XM_039084699.2 (Prss56)XR_005489287.2 (Prss56)

Sequence Details

Loading...

Expression

Primary Sources
None
Other Sources
Must provide at least one subject
Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

Molecular Interactions

1 interactor gene based on 1 annotation
Prss56 molecule type
Interactor gene
Interactor species
Interactor molecule type
Detection methods
Source
Reference
protein
UbcRattus norvegicus
protein
  • affinity chromatography technology
PMID:22871113
Showing 1 - 1 of 1 rows
per page

Genetic Interactions

No data available