Version: 8.0.0
Date: Tue Jan 28 2025
Steep1
Rattus norvegicusRGD:1564541
SummaryOrthologyParalogyFunction - GO AnnotationsPathwaysPhenotypesDisease AssociationsAlleles and VariantsTransgenic AllelesModelsSequence Feature ViewerSequence DetailsExpressionMolecular InteractionsGenetic Interactions
Gene

Steep1

Species
Rattus norvegicus
Symbol
Steep1
Name
STING1 ER exit protein 1
Synonyms
  • hypothetical protein LOC313433
  • LOC313433
Biotype
protein coding gene
Automated Description
Predicted to enable protein-macromolecule adaptor activity. Predicted to be involved in endoplasmic reticulum membrane organization; endoplasmic reticulum to Golgi vesicle-mediated transport; and protein exit from endoplasmic reticulum. Predicted to be located in several cellular components, including cell body; centrosome; and nucleoplasm. Predicted to be active in endoplasmic reticulum membrane. Human ortholog(s) of this gene implicated in non-syndromic X-linked intellectual disability 107. Orthologous to human STEEP1 (STING1 ER exit protein 1).
RGD Description
Predicted to enable protein-macromolecule adaptor activity. Predicted to be involved in endoplasmic reticulum membrane organization; endoplasmic reticulum to Golgi vesicle-mediated transport; and protein exit from endoplasmic reticulum. Predicted to be located in several cellular components, including cell body; centrosome; and nucleoplasm. Predicted to be active in endoplasmic reticulum membrane. Human ortholog(s) of this gene implicated in non-syndromic X-linked intellectual disability 107. Orthologous to human STEEP1 (STING1 ER exit protein 1); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; acrylamide; amitrole.
Cross References
Additional Information
Literature

Orthology

Gene tree
PANTHER:PTHR46355
Links to orthology data in JBrowse by filter level: Stringent,  Moderate,  No filter,  Best and Best Reverse

Paralogy

No paralogs for the gene.

Function - GO Annotations

Pathways

No data available

Phenotypes

Primary Sources
None
Other Sources
None
No data available

Disease Associations

Cases where the expected disease association was NOT found
Must provide at least one subject
Cell color indicative of annotation volume
No data available

Alleles and Variants

Allele/Variant Symbol
Allele Synonyms
Category
Variant
Variant type
Molecular consequence
Has Disease Annotations
Has Phenotype Annotations
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    Transgenic Alleles

    Species
    (carrying the transgene)
    Allele symbol
    Transgenic construct
    Expressed components
    Knock-down targets
    Regulatory regions
    Has Disease Annotations
    Has Phenotype Annotations
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      Models

      Model name
      Experimental condition
      Associated Human Diseases
      Associated Phenotypes
      Modifier
      Source
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        Sequence Feature Viewer

        Genome location
        Assembly version
        mRatBN7.2
        Viewer Help
        Data currently unavailable; sequence viewer under construction

        Sequence Details

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        Expression

        Primary Sources
        None
        Other Sources
        Must provide at least one subject
        Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

        Molecular Interactions

        Steep1 molecule type
        Interactor gene
        Interactor species
        Interactor molecule type
        Detection methods
        Source
        Reference
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          Genetic Interactions

          Steep1 role
          Steep1 genetic perturbation
          Interactor gene
          Interactor species
          Interactor role
          Interactor genetic perturbation
          Interaction type
          Phenotype or trait
          Source
          Reference
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