Gene

Onecut2

Species
Rattus norvegicus
Symbol
Onecut2
Name
one cut homeobox 2
Synonyms
  • LOC307376
  • one cut domain family member 2
Biotype
protein coding gene
Automated Description
Predicted to enable DNA-binding transcription activator activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to act upstream of or within several processes, including negative regulation of transforming growth factor beta receptor signaling pathway; peripheral nervous system neuron development; and positive regulation of mesenchymal stem cell migration. Predicted to be located in actin cytoskeleton and nucleoplasm. Predicted to be active in nucleus. Orthologous to human ONECUT2 (one cut homeobox 2).
RGD Description
Predicted to enable DNA-binding transcription activator activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to act upstream of or within several processes, including negative regulation of transforming growth factor beta receptor signaling pathway; peripheral nervous system neuron development; and positive regulation of mesenchymal stem cell migration. Predicted to be located in actin cytoskeleton and nucleoplasm. Orthologous to human ONECUT2 (one cut homeobox 2); INTERACTS WITH (+)-schisandrin B; 17beta-estradiol; 6-propyl-2-thiouracil.
Cross References
Additional Information
Literature

Orthology

Gene tree
PANTHER:PTHR14057
Links to orthology data in JBrowse by filter level: Stringent,  Moderate,  No filter,  Best and Best Reverse

Paralogy

Function - GO Annotations

Pathways

No data available

Phenotypes

Primary Sources
None
Other Sources
None

Disease Associations

Cases where the expected disease association was NOT found
Cell color indicative of annotation volume

Transgenic Alleles

Models

Sequence Feature Viewer

Genome location
Assembly version
mRatBN7.2
Viewer Help
57.84M57.85M57.86M57.87M57.88M57.89M

Sequence Details

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Expression

Primary Sources
None
Other Sources
Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

Molecular Interactions

Genetic Interactions