Gene

Heatr1

Species
Rattus norvegicus
Symbol
Heatr1
Name
HEAT repeat containing 1
Synonyms
  • HEAT repeat containing 1-like 1
  • HEAT repeat-containing protein 1
Biotype
protein coding gene
Automated Description
Predicted to enable snoRNA binding activity. Predicted to be involved in several processes, including maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA); positive regulation of RNA metabolic process; and protein localization to nucleolus. Predicted to be located in fibrillar center and mitochondrion. Predicted to be part of 90S preribosome; small-subunit processome; and t-UTP complex. Human ortholog(s) of this gene implicated in pancreatic ductal carcinoma. Orthologous to human HEATR1 (HEAT repeat containing 1).
RGD Description
Predicted to enable snoRNA binding activity. Predicted to be involved in several processes, including maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA); positive regulation of RNA metabolic process; and protein localization to nucleolus. Predicted to be located in fibrillar center and mitochondrion. Predicted to be part of 90S preribosome; small-subunit processome; and t-UTP complex. Human ortholog(s) of this gene implicated in pancreatic ductal carcinoma. Orthologous to human HEATR1 (HEAT repeat containing 1); PARTICIPATES IN ribosome biogenesis pathway; INTERACTS WITH (+)-schisandrin B; 2,4-dinitrotoluene; 2,6-dinitrotoluene.
Cross References
Additional Information
Literature

Orthology

Gene tree
PANTHER:PTHR13457
Links to orthology data in JBrowse by filter level: Stringent,  Moderate,  No filter,  Best and Best Reverse

Paralogy

Function - GO Annotations

Pathways

No data available

Phenotypes

Primary Sources
None
Other Sources
None

Disease Associations

Cases where the expected disease association was NOT found
Cell color indicative of annotation volume

Transgenic Alleles

Models

Sequence Feature Viewer

Genome location
Assembly version
mRatBN7.2
Viewer Help
58.055M58.060M58.065M58.070M58.075M58.080M58.085M58.090M

Sequence Details

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Expression

Primary Sources
None
Other Sources
Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

Molecular Interactions

Genetic Interactions