Gene

Phip

Species
Rattus norvegicus
Symbol
Phip
Name
pleckstrin homology domain interacting protein
Synonyms
  • hypothetical protein LOC315843
  • LOC315843
Biotype
protein coding gene
Automated Description
Predicted to enable lysine-acetylated histone binding activity. Predicted to be involved in several processes, including positive regulation of insulin-like growth factor receptor signaling pathway; positive regulation of mitotic nuclear division; and regulation of DNA-templated transcription. Predicted to act upstream of or within several processes, including insulin receptor signaling pathway; positive regulation of cell population proliferation; and positive regulation of macromolecule metabolic process. Predicted to be active in nucleus. Orthologous to human PHIP (pleckstrin homology domain interacting protein).
RGD Description
Predicted to enable lysine-acetylated histone binding activity. Predicted to be involved in several processes, including positive regulation of insulin-like growth factor receptor signaling pathway; positive regulation of mitotic nuclear division; and regulation of DNA-templated transcription. Predicted to act upstream of or within several processes, including insulin receptor signaling pathway; positive regulation of cell population proliferation; and positive regulation of protein phosphorylation. Predicted to be active in nucleus. Orthologous to human PHIP (pleckstrin homology domain interacting protein); INTERACTS WITH 17alpha-ethynylestradiol; 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine.
Cross References
Additional Information
Literature

Orthology

Gene tree
PANTHER:PTHR16266
Links to orthology data in JBrowse by filter level: Stringent,  Moderate,  No filter,  Best and Best Reverse

Paralogy

Function - GO Annotations

Pathways

No data available

Phenotypes

Primary Sources
None
Other Sources
None

Disease Associations

Cases where the expected disease association was NOT found
Cell color indicative of annotation volume

Transgenic Alleles

Models

Sequence Feature Viewer

Genome location
Assembly version
mRatBN7.2
Viewer Help
83.78M83.80M83.82M83.84M83.86M83.88M

Sequence Details

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Expression

Primary Sources
None
Other Sources
Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

Molecular Interactions

Genetic Interactions