Gene

Acd

Species
Rattus norvegicus
Symbol
Acd
Name
ACD, shelterin complex subunit and telomerase recruitment factor
Synonyms
  • adrenocortical dysplasia
  • adrenocortical dysplasia homolog
Biotype
protein coding gene
Automated Description
Predicted to enable DNA polymerase binding activity; telomerase inhibitor activity; and telomeric DNA binding activity. Predicted to be involved in several processes, including establishment of protein localization; negative regulation of telomere maintenance via telomerase; and telomere organization. Predicted to act upstream of or within several processes, including embryonic limb morphogenesis; telomere maintenance; and urogenital system development. Predicted to be located in chromosome, telomeric region and nuclear body. Predicted to be part of shelterin complex. Human ortholog(s) of this gene implicated in autosomal dominant dyskeratosis congenita 6. Orthologous to human ACD (ACD shelterin complex subunit and telomerase recruitment factor).
RGD Description
Predicted to enable DNA polymerase binding activity; telomerase inhibitor activity; and telomeric DNA binding activity. Predicted to be involved in several processes, including establishment of protein localization; negative regulation of telomere maintenance via telomerase; and telomere organization. Predicted to act upstream of or within several processes, including embryonic limb morphogenesis; telomere maintenance; and urogenital system development. Predicted to be located in chromosome, telomeric region and nuclear body. Predicted to be part of shelterin complex. Human ortholog(s) of this gene implicated in autosomal dominant dyskeratosis congenita 6. Orthologous to human ACD (ACD shelterin complex subunit and telomerase recruitment factor); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 4,4'-sulfonyldiphenol; bisphenol A.
Cross References
Additional Information
Literature

Orthology

Gene tree
PANTHER:PTHR14487
Links to orthology data in JBrowse by filter level: Stringent,  Moderate,  No filter,  Best and Best Reverse

Paralogy

Function - GO Annotations

Pathways

No data available

Phenotypes

Primary Sources
None
Other Sources
None

Disease Associations

Cases where the expected disease association was NOT found
Cell color indicative of annotation volume

Transgenic Alleles

Models

Sequence Feature Viewer

Genome location
Assembly version
mRatBN7.2
Viewer Help
33.5870M33.5875M33.5880M33.5885M33.5890M

Sequence Details

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Expression

Primary Sources
None
Other Sources
Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

Molecular Interactions

Genetic Interactions