Predicted to be an extracellular matrix structural constituent conferring tensile strength. Predicted to be involved in extracellular matrix organization. Predicted to act upstream of or within collagen-activated tyrosine kinase receptor signaling pathway and neuromuscular junction development. Predicted to be located in basement membrane and neuromuscular junction. Predicted to be part of collagen type IV trimer. Predicted to be active in collagen-containing extracellular matrix and extracellular space. Used to study proteinuria. Human ortholog(s) of this gene implicated in Alport syndrome and X-linked Alport syndrome. Orthologous to human COL4A5 (collagen type IV alpha 5 chain).
RGD Description
Predicted to be an extracellular matrix structural constituent conferring tensile strength. Predicted to be involved in extracellular matrix organization. Predicted to act upstream of or within collagen-activated tyrosine kinase receptor signaling pathway and neuromuscular junction development. Predicted to be located in neuromuscular junction. Predicted to be part of collagen type IV trimer. Predicted to be active in basement membrane and extracellular space. Used to study proteinuria. Human ortholog(s) of this gene implicated in Alport syndrome and X-linked Alport syndrome. Orthologous to human COL4A5 (collagen type IV alpha 5 chain); PARTICIPATES IN syndecan signaling pathway; cell-extracellular matrix signaling pathway; Entamoebiasis pathway; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 3,3',4,4',5-pentachlorobiphenyl; 6-propyl-2-thiouracil.