Gene

Col4a5

Species
Rattus norvegicus
Symbol
Col4a5
Name
collagen type IV alpha 5 chain
Synonyms
  • collagen alpha-5(IV) chain
  • collagen, type IV, alpha 5
Biotype
protein coding gene
Automated Description
Predicted to be an extracellular matrix structural constituent conferring tensile strength. Predicted to be involved in extracellular matrix organization. Predicted to act upstream of or within collagen-activated tyrosine kinase receptor signaling pathway and neuromuscular junction development. Predicted to be located in basement membrane and neuromuscular junction. Predicted to be part of collagen type IV trimer. Predicted to be active in collagen-containing extracellular matrix and extracellular space. Used to study proteinuria. Human ortholog(s) of this gene implicated in Alport syndrome and X-linked Alport syndrome. Orthologous to human COL4A5 (collagen type IV alpha 5 chain).
RGD Description
Predicted to be an extracellular matrix structural constituent conferring tensile strength. Predicted to be involved in extracellular matrix organization. Predicted to act upstream of or within collagen-activated tyrosine kinase receptor signaling pathway and neuromuscular junction development. Predicted to be located in neuromuscular junction. Predicted to be part of collagen type IV trimer. Predicted to be active in basement membrane and extracellular space. Used to study proteinuria. Human ortholog(s) of this gene implicated in Alport syndrome and X-linked Alport syndrome. Orthologous to human COL4A5 (collagen type IV alpha 5 chain); PARTICIPATES IN syndecan signaling pathway; cell-extracellular matrix signaling pathway; Entamoebiasis pathway; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 3,3',4,4',5-pentachlorobiphenyl; 6-propyl-2-thiouracil.
Cross References
Additional Information
Literature

Orthology

Gene tree
PANTHER:PTHR24023
Links to orthology data in JBrowse by filter level: Stringent,  Moderate,  No filter,  Best and Best Reverse

Paralogy

Function - GO Annotations

Pathways

No data available

Phenotypes

Primary Sources
Other Sources
None

Disease Associations

Cases where the expected disease association was NOT found
Cell color indicative of annotation volume

Transgenic Alleles

Models

Sequence Feature Viewer

Genome location
Assembly version
mRatBN7.2
Viewer Help
105.12M105.14M105.16M105.18M105.20M105.22M105.24M105.26M105.28M105.30M105.32M

Sequence Details

Loading...

Expression

Primary Sources
None
Other Sources
Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

Molecular Interactions

Genetic Interactions