Predicted to enable enzyme activator activity. Predicted to be involved in DNA metabolic process and regulation of telomere maintenance. Predicted to act upstream of or within response to intra-S DNA damage checkpoint signaling. Predicted to be located in several cellular components, including chromosome; cytosol; and nucleoplasm. Predicted to be part of ERCC4-ERCC1 complex; Holliday junction resolvase complex; and Slx1-Slx4 complex. Human ortholog(s) of this gene implicated in Fanconi anemia complementation group P. Orthologous to human SLX4 (SLX4 structure-specific endonuclease subunit).
RGD Description
Predicted to enable enzyme activator activity. Predicted to be involved in DNA metabolic process and regulation of telomere maintenance. Predicted to act upstream of or within response to intra-S DNA damage checkpoint signaling. Predicted to be located in several cellular components, including chromosome; cytosol; and nucleoplasm. Predicted to be part of ERCC4-ERCC1 complex; Holliday junction resolvase complex; and Slx1-Slx4 complex. Human ortholog(s) of this gene implicated in Fanconi anemia complementation group P. Orthologous to human SLX4 (SLX4 structure-specific endonuclease subunit); INTERACTS WITH 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine; 6-propyl-2-thiouracil.