Predicted to enable chromatin binding activity; histone H3K14 acetyltransferase activity; and transcription coactivator activity. Involved in positive regulation of transcription by RNA polymerase II. Predicted to be located in chromatin. Predicted to be part of MOZ/MORF histone acetyltransferase complex. Predicted to be active in nucleus. Human ortholog(s) of this gene implicated in Ohdo syndrome, SBBYS variant; bipolar disorder; breast cancer; and leiomyoma. Orthologous to human KAT6B (lysine acetyltransferase 6B).
RGD Description
Predicted to enable histone H3K14 acetyltransferase activity and transcription coactivator activity. Involved in positive regulation of transcription by RNA polymerase II. Predicted to be located in nucleus. Predicted to be part of MOZ/MORF histone acetyltransferase complex. Human ortholog(s) of this gene implicated in Ohdo syndrome, SBBYS variant; bipolar disorder; breast cancer; and leiomyoma. Orthologous to human KAT6B (lysine acetyltransferase 6B); PARTICIPATES IN histone modification pathway; INTERACTS WITH 17beta-estradiol; 4,4'-sulfonyldiphenol; atrazine.