Gene

Kat6b

Species
Rattus norvegicus
Symbol
Kat6b
Name
lysine acetyltransferase 6B
Synonyms
  • histone acetyltransferase KAT6B
  • K(lysine) acetyltransferase 6B
Biotype
protein coding gene
Automated Description
Predicted to enable chromatin binding activity; histone H3K14 acetyltransferase activity; and transcription coactivator activity. Involved in positive regulation of transcription by RNA polymerase II. Predicted to be located in chromatin. Predicted to be part of MOZ/MORF histone acetyltransferase complex. Predicted to be active in nucleus. Human ortholog(s) of this gene implicated in Ohdo syndrome, SBBYS variant; bipolar disorder; breast cancer; and leiomyoma. Orthologous to human KAT6B (lysine acetyltransferase 6B).
RGD Description
Predicted to enable histone H3K14 acetyltransferase activity and transcription coactivator activity. Involved in positive regulation of transcription by RNA polymerase II. Predicted to be located in nucleus. Predicted to be part of MOZ/MORF histone acetyltransferase complex. Human ortholog(s) of this gene implicated in Ohdo syndrome, SBBYS variant; bipolar disorder; breast cancer; and leiomyoma. Orthologous to human KAT6B (lysine acetyltransferase 6B); PARTICIPATES IN histone modification pathway; INTERACTS WITH 17beta-estradiol; 4,4'-sulfonyldiphenol; atrazine.
Cross References
Additional Information
Literature

Orthology

Gene tree
PANTHER:PTHR10615
Links to orthology data in JBrowse by filter level: Stringent,  Moderate,  No filter,  Best and Best Reverse

Paralogy

Function - GO Annotations

Pathways

No data available

Phenotypes

Primary Sources
None
Other Sources
None

Disease Associations

Cases where the expected disease association was NOT found
Must provide at least one subject
Cell color indicative of annotation volume

Transgenic Alleles

No data available

Models

No data available

Sequence Feature Viewer

Genome location
Assembly version
mRatBN7.2
Viewer Help
2.64M2.66M2.68M2.70M2.72M2.74M2.76M2.78M2.80M

Sequence Details

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Expression

Primary Sources
None
Other Sources
Must provide at least one subject
Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

Molecular Interactions

Genetic Interactions