Gene

Foxl1

Species
Rattus norvegicus
Symbol
Foxl1
Name
forkhead box L1
Synonyms
  • forkhead box protein L1
  • LOC687553
Biotype
protein coding gene
Automated Description
Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in several processes, including cell differentiation; heart development; and regulation of transcription by RNA polymerase II. Predicted to act upstream of or within several processes, including Peyer's patch morphogenesis; proteoglycan biosynthetic process; and visceral mesoderm-endoderm interaction involved in midgut development. Predicted to be located in nucleus. Human ortholog(s) of this gene implicated in otosclerosis 11. Orthologous to human FOXL1 (forkhead box L1).
RGD Description
Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in several processes, including cell differentiation; heart development; and regulation of transcription by RNA polymerase II. Predicted to act upstream of or within several processes, including Peyer's patch morphogenesis; proteoglycan biosynthetic process; and visceral mesoderm-endoderm interaction involved in midgut development. Predicted to be located in nucleus. Human ortholog(s) of this gene implicated in otosclerosis 11. Orthologous to human FOXL1 (forkhead box L1); INTERACTS WITH trichloroethene; 17beta-estradiol (ortholog); 2,3,7,8-tetrachlorodibenzodioxine (ortholog).
Cross References
Additional Information
Literature

Orthology

Gene tree
PANTHER:PTHR11829
Links to orthology data in JBrowse by filter level: Stringent,  Moderate,  No filter,  Best and Best Reverse

Paralogy

Function - GO Annotations

Pathways

No data available

Phenotypes

Primary Sources
None
Other Sources
None

Disease Associations

Cases where the expected disease association was NOT found
Cell color indicative of annotation volume

Transgenic Alleles

Models

Sequence Feature Viewer

Genome location
Assembly version
mRatBN7.2
Viewer Help
49.1975M49.1980M49.1985M49.1990M49.1995M49.2000M49.2005M

Sequence Details

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Expression

Primary Sources
None
Other Sources
Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

Molecular Interactions

Genetic Interactions