Gene

Jmy

Species
Rattus norvegicus
Symbol
Jmy
Name
junction mediating and regulatory protein, p53 cofactor
Synonyms
  • junction mediating and regulatory protein
  • LOC683593
Biotype
protein coding gene
Automated Description
Predicted to enable Arp2/3 complex binding activity; microtubule binding activity; and transcription coactivator activity. Predicted to be involved in several processes, including actin nucleation; actin polymerization-dependent cell motility; and intrinsic apoptotic signaling pathway by p53 class mediator. Predicted to act upstream of or within regulation of transcription by RNA polymerase II. Predicted to be located in autophagosome membrane; cell leading edge; and cytoplasmic vesicle. Predicted to be active in cytoplasm and nucleus. Orthologous to human JMY (junction mediating and regulatory protein, p53 cofactor).
RGD Description
Predicted to enable microtubule binding activity and transcription coactivator activity. Predicted to be involved in several processes, including actin nucleation; actin polymerization-dependent cell motility; and cellular response to starvation. Predicted to act upstream of or within intrinsic apoptotic signaling pathway by p53 class mediator and regulation of transcription by RNA polymerase II. Predicted to be located in several cellular components, including autophagosome membrane; cell leading edge; and cytoplasmic vesicle. Orthologous to human JMY (junction mediating and regulatory protein, p53 cofactor); INTERACTS WITH 17alpha-ethynylestradiol; 4,4'-diaminodiphenylmethane; amphetamine.
Cross References
Additional Information
Literature

Orthology

Gene tree
PANTHER:PTHR23330
Links to orthology data in JBrowse by filter level: Stringent,  Moderate,  No filter,  Best and Best Reverse

Paralogy

Function - GO Annotations

Pathways

No data available

Phenotypes

Primary Sources
None
Other Sources
None

Disease Associations

Cases where the expected disease association was NOT found
Cell color indicative of annotation volume

Transgenic Alleles

Models

Sequence Feature Viewer

Genome location
Assembly version
mRatBN7.2
Viewer Help
24.67M24.68M24.69M24.70M24.71M24.72M24.73M

Sequence Details

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Expression

Primary Sources
None
Other Sources
Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

Molecular Interactions

Genetic Interactions