Gene

Spaca4

Species
Rattus norvegicus
Symbol
Spaca4
Name
sperm acrosome associated 4
Synonyms
  • LOC691120
  • similar to sperm acrosomal membrane protein 14
Biotype
protein coding gene
Automated Description
Predicted to be involved in binding activity of sperm to zona pellucida. Predicted to be located in inner acrosomal membrane and outer acrosomal membrane. Predicted to be active in membrane. Orthologous to human SPACA4 (sperm acrosome associated 4).
RGD Description
Predicted to be involved in sperm-egg recognition. Predicted to be located in plasma membrane. Predicted to be active in membrane. Orthologous to human SPACA4 (sperm acrosome associated 4); INTERACTS WITH bisphenol A; C60 fullerene; 17beta-estradiol (ortholog).
Cross References
Additional Information
Literature

Orthology

Gene tree
PANTHER:PTHR47613
Stringency:
Additional filters to further constrain the results:
Species Gene symbol Count Best Best reverse
Method
Ensembl ComparaHGNCHieranoidInParanoidOMAOrthoFinderOrthoInspectorPANTHERPhylomeDBSonicParanoidXenbaseZFIN
Homo sapiensSPACA410 of 10YesYes  
Mus musculusSpaca49 of 9YesYes   
Danio reriospaca4l4 of 9YesYes   
Links to orthology data in JBrowse by filter level: Stringent,  Moderate,  No filter,  Best and Best Reverse

Paralogy

No paralogs for the gene.

Function - GO Annotations

No function available for that gene

Pathways

No data available

Phenotypes

Primary Sources
None
Other Sources
None
No data available

Disease Associations

Cases where the expected disease association was NOT found
all annotationsall disease by infectious agentbacterial infectious diseasefungal infectious diseaseparasitic infectious diseaseviral infectious diseaseall disease of anatomical entitycardiovascular system diseasecentral nervous system diseaseendocrine system diseasegastrointestinal system diseasehematopoietic system diseaseimmune system diseaseintegumentary system diseasemusculoskeletal system diseaseperipheral nervous system diseasereproductive system diseaserespiratory system diseasesensory system diseasethoracic diseaseurinary system diseaseall disease of cellular proliferationbenign neoplasmcancerpre-malignant neoplasmall genetic diseasechromosomal diseasemonogenic diseasepolygenic diseaseall other diseasedisease of mental healthdisease of metabolismphysical disordersyndrome
Spaca4 (Rno)
SPACA4 (Hsa)
Spaca4 (Mmu)
spaca4l (Dre)
Cell color indicative of annotation volume
No data available

Alleles and Variants

Genome location
Assembly version
mRatBN7.2
Viewer Help
96.1954M96.1955M96.1956M96.1957M96.1958M96.1959M96.1960M96.1961M96.1962M
Variant Types and ConsequencesOnly variants associated to alleles are shown in the graphics above. See all variants in JBrowse.
Allele/Variant Symbol
Allele Synonyms
Category
Variant
Variant type
Molecular consequence
Has Disease Annotations
Has Phenotype Annotations
NC_051336.1:g.96195938A>Tvariant
SNP
  • synonymous variant
NC_051336.1:g.96195498T>Cvariant
SNP
  • 3 prime UTR variant
Showing 1 - 2 of 2 rows
per page

Transgenic Alleles

No data available

Models

No data available

Sequence Feature Viewer

Genome location
Assembly version
mRatBN7.2
Viewer Help
96.1954M96.1955M96.1956M96.1957M96.1958M96.1959M96.1960M96.1961M96.1962MENSRNOT00000028558.4 (Spaca4)NM_001109623.1 (Spaca4)ENSRNOT00000028564.6 (Fam83e)

Sequence Details

Transcript: Mode:

Expression

Primary Sources
None
Other Sources
all annotationsall anatomical structuresalimentary part of gastrointestinal systemchemosensory systemcirculatory systemendocrine systemexocrine systemhemolymphoid systemhepatobiliary systemintegumental systemmechanosensory systemmusculoskeletal systemnervous systemrenal systemreproductive systemrespiratory systemsensory systemvestibulo-auditory systemvisual systemendodermectodermmesodermmesenchymeadipose tissueappendageentire extraembryonic componentimaginal precursorpharyngeal archotherall stagesembryo stagepost embryonic, pre-adultpost-juvenile adult stageall cellular componentsextracellular regionplasma membranesynapsecell junctioncell projectioncytoplasmic vesicleendosomevacuolegolgi apparatusendoplasmic reticulumcytosolmitochondrionnucleuschromosomecytoskeletonprotein-containing complexother locations
Spaca4 (Rno)
spaca4l (Dre)
Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

Molecular Interactions

No data available

Genetic Interactions

No data available