Gene

Krt6c

Species
Rattus norvegicus
Symbol
Krt6c
Name
keratin 6c
Synonyms
  • CK 6A
  • CK-6A
Biotype
protein coding gene
Automated Description
Predicted to be a structural constituent of skin epidermis. Predicted to be involved in several processes, including intermediate filament organization; keratinization; and wound healing. Predicted to be active in keratin filament. Human ortholog(s) of this gene implicated in focal or diffuse nonepidermolytic palmoplantar keratoderma and pachyonychia congenita. Orthologous to human KRT6A (keratin 6A); KRT6B (keratin 6B); and KRT6C (keratin 6C).
RGD Description
Predicted to be a structural constituent of skin epidermis. Predicted to be involved in several processes, including intermediate filament organization; keratinization; and wound healing. Predicted to be active in keratin filament. Human ortholog(s) of this gene implicated in focal or diffuse nonepidermolytic palmoplantar keratoderma and pachyonychia congenita. Orthologous to human KRT6A (keratin 6A); KRT6B (keratin 6B); and KRT6C (keratin 6C); INTERACTS WITH 1-chloro-2,4-dinitrobenzene (ortholog); 17beta-estradiol (ortholog); 2-palmitoylglycerol (ortholog).
Cross References
Additional Information
Literature

Orthology

Gene tree
PANTHER:PTHR45616
Links to orthology data in JBrowse by filter level: Stringent,  Moderate,  No filter,  Best and Best Reverse

Paralogy

Function - GO Annotations

Pathways

No data available

Phenotypes

Primary Sources
None
Other Sources
None

Disease Associations

Cases where the expected disease association was NOT found
Cell color indicative of annotation volume

Transgenic Alleles

Models

Sequence Feature Viewer

Genome location
Assembly version
mRatBN7.2
Viewer Help
132.8000M132.8005M132.8010M132.8015M132.8020M132.8025M132.8030M132.8035M132.8040M

Sequence Details

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Expression

Primary Sources
None
Other Sources
Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

Molecular Interactions

Genetic Interactions