Gene

Rnf5

Species
Rattus norvegicus
Symbol
Rnf5
Name
ring finger protein 5
Synonyms
  • E3 ubiquitin-protein ligase RNF5
  • ing finger protein 5 pseudogene
Biotype
protein coding gene
Automated Description
Predicted to enable identical protein binding activity; ubiquitin protein ligase activity; and ubiquitin-like protein conjugating enzyme binding activity. Predicted to be involved in protein polyubiquitination and proteolysis involved in protein catabolic process. Predicted to act upstream of or within several processes, including negative regulation of autophagy; protein destabilization; and regulation of autophagosome assembly. Predicted to be located in endoplasmic reticulum and membrane. Orthologous to human RNF5 (ring finger protein 5).
RGD Description
Predicted to enable identical protein binding activity; ubiquitin protein ligase activity; and ubiquitin-like protein conjugating enzyme binding activity. Predicted to be involved in protein polyubiquitination and proteolysis involved in protein catabolic process. Predicted to act upstream of or within several processes, including negative regulation of autophagy; protein destabilization; and regulation of autophagosome assembly. Predicted to be located in endoplasmic reticulum and membrane. Orthologous to human RNF5 (ring finger protein 5); PARTICIPATES IN Endoplasmic Reticulum-associated degradation pathway; INTERACTS WITH 2-methoxyethanol; acrylamide; bisphenol A.
Cross References
Additional Information
Literature

Orthology

Gene tree
PANTHER:PTHR12313
Links to orthology data in JBrowse by filter level: Stringent,  Moderate,  No filter,  Best and Best Reverse

Paralogy

Function - GO Annotations

Pathways

No data available

Phenotypes

Primary Sources
None
Other Sources
None

Disease Associations

Cases where the expected disease association was NOT found
Cell color indicative of annotation volume

Transgenic Alleles

Models

Sequence Feature Viewer

Genome location
Assembly version
mRatBN7.2
Viewer Help
4.1456M4.1458M4.1460M4.1462M4.1464M4.1466M4.1468M4.1470M4.1472M4.1474M4.1476M4.1478M

Sequence Details

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Expression

Primary Sources
None
Other Sources
Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

Molecular Interactions

Genetic Interactions