Gene

Acer1

Species
Rattus norvegicus
Symbol
Acer1
Name
alkaline ceramidase 1
Synonyms
  • Asah3
  • LOC301118
Biotype
protein coding gene
Automated Description
Predicted to enable N-acylsphingosine amidohydrolase activity. Predicted to be involved in several processes, including keratinocyte differentiation; response to alkaline pH; and sphingolipid metabolic process. Predicted to act upstream of or within regulation of lipid metabolic process and sphingolipid metabolic process. Predicted to be located in membrane. Predicted to be active in endoplasmic reticulum. Orthologous to human ACER1 (alkaline ceramidase 1).
RGD Description
Predicted to enable N-acylsphingosine amidohydrolase activity. Predicted to be involved in several processes, including keratinocyte differentiation; response to alkaline pH; and sphingolipid metabolic process. Predicted to act upstream of or within regulation of lipid metabolic process and sphingolipid metabolic process. Predicted to be located in membrane. Predicted to be active in endoplasmic reticulum. Orthologous to human ACER1 (alkaline ceramidase 1); PARTICIPATES IN Fabry disease pathway; Gaucher's disease pathway; Krabbe disease pathway; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,3,7,8-Tetrachlorodibenzofuran; bisphenol A.
Cross References
Additional Information
Literature

Orthology

Gene tree
PANTHER:PTHR46139
Links to orthology data in JBrowse by filter level: Stringent,  Moderate,  No filter,  Best and Best Reverse

Paralogy

Function - GO Annotations

Pathways

No data available

Phenotypes

Primary Sources
None
Other Sources
None

Disease Associations

Cases where the expected disease association was NOT found
Cell color indicative of annotation volume

Transgenic Alleles

Models

Sequence Feature Viewer

Genome location
Assembly version
mRatBN7.2
Viewer Help
1.795M1.800M1.805M1.810M1.815M1.820M

Sequence Details

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Expression

Primary Sources
None
Other Sources
Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

Molecular Interactions

Genetic Interactions