Gene

Svep1

Species
Rattus norvegicus
Symbol
Svep1
Name
sushi, von Willebrand factor type A, EGF and pentraxin domain containing 1
Synonyms
  • LOC103692362
  • LOC685899
Biotype
protein coding gene
Automated Description
Predicted to enable chromatin binding activity and integrin binding activity involved in cell-matrix adhesion. Predicted to be involved in several processes, including lymph vessel morphogenesis; negative regulation of vasoconstriction; and positive regulation of platelet activation. Predicted to act upstream of or within several processes, including Tie signaling pathway; lymph circulation; and lymph vessel development. Predicted to be located in cytoplasm; extracellular space; and nucleus. Orthologous to human SVEP1 (sushi, von Willebrand factor type A, EGF and pentraxin domain containing 1).
RGD Description
Predicted to enable chromatin binding activity and integrin binding activity involved in cell-matrix adhesion. Predicted to be involved in several processes, including negative regulation of complement activation, classical pathway; negative regulation of vasoconstriction; and positive regulation of platelet activation. Predicted to act upstream of or within several processes, including Tie signaling pathway; lymph circulation; and lymph vessel development. Predicted to be located in cytoplasm; extracellular region; and nucleus. Predicted to be active in extracellular space. Orthologous to human SVEP1 (sushi, von Willebrand factor type A, EGF and pentraxin domain containing 1); INTERACTS WITH 1-naphthyl isothiocyanate; 2,3,7,8-tetrachlorodibenzodioxine; 2,3,7,8-Tetrachlorodibenzofuran.
Cross References
Additional Information
Literature

Orthology

Gene tree
PANTHER:PTHR19325
Links to orthology data in JBrowse by filter level: Stringent,  Moderate,  No filter,  Best and Best Reverse

Paralogy

Function - GO Annotations

Pathways

No data available

Phenotypes

Primary Sources
None
Other Sources
None

Disease Associations

Cases where the expected disease association was NOT found
Cell color indicative of annotation volume

Transgenic Alleles

Models

Sequence Feature Viewer

Genome location
Assembly version
mRatBN7.2
Viewer Help
72.82M72.84M72.86M72.88M72.90M72.92M72.94M72.96M72.98M

Sequence Details

Loading...

Expression

Primary Sources
None
Other Sources
Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

Molecular Interactions

Genetic Interactions