Version: 8.0.0
Date: Tue Jan 28 2025
Atg2a
Rattus norvegicusRGD:1589890
SummaryOrthologyParalogyFunction - GO AnnotationsPathwaysPhenotypesDisease AssociationsAlleles and VariantsTransgenic AllelesModelsSequence Feature ViewerSequence DetailsExpressionMolecular InteractionsGenetic Interactions
Gene

Atg2a

Species
Rattus norvegicus
Symbol
Atg2a
Name
autophagy related 2A
Synonyms
  • ATG2 autophagy related 2 homolog A
  • ATG2 autophagy related 2 homolog A (S. cerevisiae)
Biotype
protein coding gene
Automated Description
Predicted to enable lipid transfer activity; phosphatidylinositol-3-phosphate binding activity; and protein-membrane adaptor activity. Predicted to be involved in autophagy of mitochondrion; macroautophagy; and positive regulation of autophagosome assembly. Predicted to be located in endoplasmic reticulum membrane; lipid droplet; and phagophore assembly site membrane. Predicted to be active in organelle membrane contact site; phagophore; and phagophore assembly site. Orthologous to human ATG2A (autophagy related 2A).
RGD Description
Predicted to enable lipid transfer activity; phosphatidylinositol-3-phosphate binding activity; and protein-membrane adaptor activity. Predicted to be involved in autophagy of mitochondrion; macroautophagy; and positive regulation of autophagosome assembly. Predicted to be located in endoplasmic reticulum; lipid droplet; and phagophore assembly site membrane. Predicted to be active in organelle membrane contact site; phagophore; and phagophore assembly site. Orthologous to human ATG2A (autophagy related 2A); INTERACTS WITH bisphenol A; diethylstilbestrol; methamphetamine.
Cross References
Additional Information
Literature

Orthology

Gene tree
PANTHER:PTHR13190
Stringency:
Additional filters to further constrain the results:
Species Gene symbol Count Best Best reverse
Method
Ensembl ComparaHGNCHieranoidInParanoidOMAOrthoFinderOrthoInspectorPANTHERPhylomeDBSonicParanoidXenbaseZFIN
Homo sapiensATG2A9 of 10YesYes☐☑☑☑☑☑☑☑☑☑  
Mus musculusAtg2a9 of 9YesYes☑ ☑☑☑☑☑☑☑☑  
Xenopus tropicalisatg2a8 of 9YesYes☐ ☑☑☑☑☑☑☑☑  
Danio rerioatg2a9 of 9YesYes☑ ☑☑☑☑☑☑☑☑  
Drosophila melanogasterAtg29 of 9YesYes☑ ☑☑☑☑☑☑☑☑  
Caenorhabditis elegansatg-29 of 9YesYes☑ ☑☑☑☑☑☑☑☑  
Saccharomyces cerevisiaeATG26 of 9YesYes☑ ☑☐☐☑☑☑☐☑  
Links to orthology data in JBrowse by filter level: Stringent,  Moderate,  No filter,  Best and Best Reverse

Paralogy

Gene symbolRank Alignment Length (aa) Similarity %Identity %Method Count
Method
Ensembl ComparaHGNCInParanoidOMAOrthoFinderOrthoInspectorPANTHERPhylomeDBSonicParanoidSGD
Atg2b18 of 9☑☐☑☑☑☑☑☑☑ 

Function - GO Annotations

Pathways

No data available

Phenotypes

Primary Sources
None
Other Sources
None
No data available

Disease Associations

Cases where the expected disease association was NOT found
Must provide at least one subject
Cell color indicative of annotation volume
Species
Gene
Association
Disease Qualifier
Disease
Evidence
Source
Based On
References
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    Alleles and Variants

    Genome location
    Assembly version
    mRatBN7.2
    Viewer Help
    Data currently unavailable; sequence viewer under construction
    Allele/Variant Symbol
    Allele Synonyms
    Category
    Variant
    Variant type
    Molecular consequence
    Has Disease Annotations
    Has Phenotype Annotations
    NC_051336.1:g.203546110A>Gvariant
    SNP
    • intron variant
    NC_051336.1:g.203551963A>Gvariant
    SNP
    • intron variant
    NC_051336.1:g.203561401C>Tvariant
    SNP
    • synonymous variant
    NC_051336.1:g.203561915A>Gvariant
    SNP
    • 3 prime UTR variant
    NC_051336.1:g.203544797C>Tvariant
    SNP
    • intron variant
    NC_051336.1:g.203548827G>Avariant
    SNP
    • missense variant
    NC_051336.1:g.203549526C>Tvariant
    SNP
    • synonymous variant
    NC_051336.1:g.203560679T>Cvariant
    NC_051336.1:g.203561211T>Cvariant
    SNP
    • intron variant
    NC_051336.1:g.203561539C>Tvariant
    SNP
    • splice region variant
    Showing 1 - 10 of 44 rows
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    View detailed Alleles/Variants information
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    Transgenic Alleles

    No data available

    Models

    No data available

    Sequence Feature Viewer

    Genome location
    Assembly version
    mRatBN7.2
    Viewer Help
    Data currently unavailable; sequence viewer under construction

    Sequence Details

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    Expression

    Primary Sources
    None
    Other Sources
    Must provide at least one subject
    Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

    Molecular Interactions

    No data available

    Genetic Interactions

    No data available