Gene

Vbp1

Species
Rattus norvegicus
Symbol
Vbp1
Name
VHL binding protein 1
Synonyms
  • LOC681825
  • prefoldin subunit 3
Biotype
protein coding gene
Automated Description
Predicted to enable amyloid-beta binding activity and unfolded protein binding activity. Predicted to be involved in negative regulation of amyloid fibril formation and protein folding. Predicted to be located in cytosol and intracellular membrane-bounded organelle. Predicted to be part of prefoldin complex. Orthologous to human VBP1 (VHL binding protein 1).
RGD Description
Predicted to enable amyloid-beta binding activity; tubulin binding activity; and unfolded protein binding activity. Predicted to be involved in several processes, including negative regulation of amyloid fibril formation; protein folding; and tubulin complex assembly. Predicted to be located in cytosol and intracellular membrane-bounded organelle. Predicted to be part of prefoldin complex. Predicted to be active in cytoplasm. Orthologous to human VBP1 (VHL binding protein 1); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; aconitine; bisphenol A.
Cross References
Additional Information
Literature

Orthology

Gene tree
PANTHER:PTHR12409

Paralogy

Function - GO Annotations

Pathways

No data available

Phenotypes

Primary Sources
None
Other Sources
None
Phenotype Term
Annotation details
References
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    Disease Associations

    Cases where the expected disease association was NOT found
    Cell color indicative of annotation volume
    No data available

    Alleles and Variants

    Allele/Variant Symbol
    Allele Synonyms
    Category
    Variant
    Variant type
    Molecular consequence
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      Transgenic Alleles

      Species
      (carrying the transgene)
      Allele symbol
      Transgenic construct
      Expressed components
      Knock-down targets
      Regulatory regions
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        Models

        Model name
        Experimental condition
        Associated Human Diseases
        Associated Phenotypes
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          Sequence Feature Viewer

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          Sequence Details

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          Expression

          Primary Sources
          None
          Other Sources
          Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

          Molecular Interactions

          Vbp1 molecule type
          Interactor gene
          Interactor species
          Interactor molecule type
          Detection methods
          Source
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            Genetic Interactions

            Vbp1 role
            Vbp1 genetic perturbation
            Interactor gene
            Interactor species
            Interactor role
            Interactor genetic perturbation
            Interaction type
            Phenotype or trait
            Source
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