Version: 8.1.0
Date: Fri Apr 18 2025
Spag17
Rattus norvegicusRGD:1592218
SummaryOrthologyParalogyFunction - GO AnnotationsPathwaysPhenotypesDisease AssociationsAlleles and VariantsTransgenic AllelesModelsSequence Feature ViewerSequence DetailsExpressionMolecular InteractionsGenetic Interactions
Gene

Spag17

Species
Rattus norvegicus
Symbol
Spag17
Name
sperm associated antigen 17
Synonyms
  • LOC690746
  • similar to projection protein PF6
Biotype
protein coding gene
Automated Description
Predicted to be involved in cilium assembly; epithelial cilium movement involved in extracellular fluid movement; and spermatid development. Predicted to act upstream of or within establishment of localization in cell. Predicted to be located in Golgi apparatus; acrosomal vesicle; and manchette. Predicted to be active in axonemal central apparatus. Human ortholog(s) of this gene implicated in spermatogenic failure 55. Orthologous to human SPAG17 (sperm associated antigen 17).
RGD Description
Predicted to be involved in cilium assembly; epithelial cilium movement involved in extracellular fluid movement; and spermatid development. Predicted to act upstream of or within establishment of localization in cell. Predicted to be located in Golgi apparatus; acrosomal vesicle; and manchette. Predicted to be active in axonemal central apparatus. Human ortholog(s) of this gene implicated in spermatogenic failure 55. Orthologous to human SPAG17 (sperm associated antigen 17); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,3,7,8-Tetrachlorodibenzofuran; methoxychlor.
Cross References
Additional Information
Literature

Orthology

Gene tree
PANTHER:PTHR21963
Links to orthology data in JBrowse by filter level: Stringent,  Moderate,  No filter,  Best and Best Reverse

Paralogy

Function - GO Annotations

Pathways

No data available

Phenotypes

Primary Sources
None
Other Sources
None
Phenotype Term
Annotation details
References
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    Disease Associations

    Cases where the expected disease association was NOT found
    Cell color indicative of annotation volume

    Alleles and Variants

    Allele/Variant Symbol
    Allele Synonyms
    Category
    Variant
    Variant type
    Molecular consequence
    Has Disease Annotations
    Has Phenotype Annotations
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      Download all Alleles/Variants for all genes of the species

      Transgenic Alleles

      Species
      (carrying the transgene)
      Allele symbol
      Transgenic construct
      Expressed components
      Knock-down targets
      Regulatory regions
      Has Disease Annotations
      Has Phenotype Annotations
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        Models

        Model name
        Experimental condition
        Associated Human Diseases
        Associated Phenotypes
        Modifier
        Source
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          Sequence Feature Viewer

          Genome location
          Assembly version
          mRatBN7.2
          Viewer Help
          Data currently unavailable; sequence viewer under construction

          Sequence Details

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          Expression

          Primary Sources
          None
          Other Sources
          Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

          Molecular Interactions

          Spag17 molecule type
          Interactor gene
          Interactor species
          Interactor molecule type
          Detection method
          Source
          Reference
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            Genetic Interactions

            Spag17 role
            Spag17 genetic perturbation
            Interactor gene
            Interactor species
            Interactor role
            Interactor genetic perturbation
            Interaction type
            Phenotype or trait
            Source
            Reference
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