Gene

Cdkn2d

Species
Rattus norvegicus
Symbol
Cdkn2d
Name
cyclin dependent kinase inhibitor 2D
Synonyms
  • cyclin-dependent kinase 4 inhibitor D
  • MGC109660
Biotype
protein coding gene
Automated Description
Predicted to enable cyclin-dependent protein serine/threonine kinase inhibitor activity and protein kinase binding activity. Predicted to be involved in several processes, including autophagic cell death; negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage; and regulation of phosphorylation. Predicted to act upstream of or within negative regulation of cell cycle G1/S phase transition and sensory perception of sound. Predicted to be located in cytosol and nucleoplasm. Predicted to be part of cyclin D2-CDK4 complex. Predicted to be active in nucleus.
RGD Description
Predicted to enable cyclin-dependent protein serine/threonine kinase inhibitor activity and protein kinase binding activity. Predicted to be involved in several processes, including autophagic cell death; negative regulation of apoptotic process; and regulation of phosphorylation. Predicted to act upstream of or within negative regulation of cell cycle G1/S phase transition and sensory perception of sound. Predicted to be located in cytosol and nucleoplasm. Predicted to be part of cyclin D2-CDK4 complex; PARTICIPATES IN G1/S transition pathway; cell cycle pathway, mitotic; INTERACTS WITH 1,2-dimethylhydrazine; 1,3-dinitrobenzene; bisphenol A.
Cross References
Additional Information
Literature

Orthology

Gene tree
PANTHER:PTHR24201
Links to orthology data in JBrowse by filter level: Stringent,  Moderate,  No filter,  Best and Best Reverse

Paralogy

Function - GO Annotations

Pathways

No data available

Phenotypes

Primary Sources
None
Other Sources
None

Disease Associations

Cases where the expected disease association was NOT found
Cell color indicative of annotation volume

Transgenic Alleles

Models

Sequence Feature Viewer

Genome location
Assembly version
mRatBN7.2
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19.8320M19.8325M19.8330M19.8335M19.8340M19.8345M

Sequence Details

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Expression

Primary Sources
None
Other Sources
Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

Molecular Interactions

Genetic Interactions